Skip to main content

Table 3 Univariate and multivariate analysis of variable factors for 5-year local recurrence free survival (LRFS)

From: Radiographic response to neoadjuvant therapy and its impact on scope of surgery and prognosis in stage IIB/III soft tissue sarcomas

Factors LRFS Univariate analysis Multivariate analysis
RR 95% CI P RR 95% CI P
Radiographic response     0.024    0.351
 PR (n = 25) 96.0 0.100 0.014-0.737   0.366 0.044-3.027  
 SD + PD (n = 95) 65.0 1    1   
Size (cm)     <0.001    0.572
 ≥10 (n = 63) 33.3 6.614 2.293-19.079   1.491 0.373-5.950  
 <10 (n = 57) 81.4 1    1   
FNCLCC Grade     <0.001    0.120
 Grade 2 (n = 45) 86.2 1    1   
 Grade 3 (n = 75) 38.6 9.178 2.177-38.697   3.278 0.734-14.649  
UICC margins     <0.001    <0.001
 R0 + R1 (n = 92) 69.9 1    1   
 R2 (n = 28) 6.6 22.975 9.204-57.353   10.458 3.755-29.126  
Surgery type     <0.001    0.672
 Resection only (n = 55) 89.4 1    1   
 Resection with other modalities* (n = 65) 27.1 9.184 2.767-30.476   1.431 0.273-7.498  
  1. *: Other modalities include epineural dissection and reconstruction of blood vessels and bony structures. FNCLCC: French Federation of Cancer Centres; UICC: Union Internationale Contre Cancer.