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Table 2 Univariate and multivariate analysis of variable factors for 5-year OS

From: Radiographic response to neoadjuvant therapy and its impact on scope of surgery and prognosis in stage IIB/III soft tissue sarcomas

Factors OS Univariate analysis Multivariate analysis
RR 95% CI P RR 95% CI P
Radiographic response     <0.001    
 PR (n = 25) 96.0 0.081 0.027-0.239   0.133 0.037-0.483 0.002
 SD + PD (n = 95) 38.8 1    1   
Size (cm)     <0.001    0.568
 ≥10 (n = 63) 33.5 5.276 2.704-10.294   1.263 0.566-2.818  
 <10 (n = 57) 81.4 1    1   
FNCLCC Grade     <0.001    0.001
 Grade 2 (n = 45) 86.2 1    1   
 Grade 3 (n = 75) 38.7 6.188 2.647-14.467   5.146 2.028-13.058  
UICC margins     <0.001    0.005
 R0 + R1 (n = 92) 69.9 1    1   
 R2 (n = 28) 6.6 8.196 4.604-14.591   2.384 1.301-4.367  
Surgery type     <0.001    0.027
 Resection only (n = 55) 89.4 1    1   
 Resection with other modalities* (n = 65) 26.9 9.708 4.479-21.042   2.986 1.133-7.865  
  1. *: Other modalities include epineural dissection and reconstruction of blood vessels and bony structures. FNCLCC: French Federation of Cancer Centres; UICC: Union Internationale Contre Cancer.