Figure 3
From: IL-22 is related to development of human colon cancer by activation of STAT3
IL-22 related proteins are also over-expressed in human colon cancer and ulcerative colitis. A1-A3: Average integrated optical density (IOD) was obtained by analyzing five fields for each slide evaluated by Image-Pro Plus software (version 5.0) for IHC staining of IL-23, IL-22RA1, and p-STAT3 (S727) in human CC, UC, and normal colon tissues. B1-3, B4-6 and B7-B9: Expression and distribution of IL-23, IL-22RA1 and p-STAT3 (S727) in human CC (n = 84), UC (n = 40) and normal colon tissues (n = 40) respectively (Mann–Whitney U test). * represented P < 0.05 and ** represented P < 0.01.