Up-regulation of CLDN1 in gastric cancer is correlated with reduced survival

BMC Cancer

Table 5 KEGG cellular signaling pathways

Rank	Pathway name	IF	P-value
1	Cell adhesion molecules (CAMs)	734.0	0.000129
2	Leukocyte transendothelial migration	672.1	0.000879
3	ECM-receptor interaction	10.9	0.00215
4	Tight junction	10.6	0.000296
5	Epithelial cell signaling in Helicobacter	7.2	0.006
6	TGF-beta signaling pathway	6.3	0.013
7	Focal adhesion	6.2	0.014
8	Calcium signaling pathway	5.1	0.035

Significantly enriched KEGG cellular signaling pathways in the dataset (p < 0.05). Impact Factor (IF) is used to rank the affected signaling pathways, based on the fold change, the number of the involved genes in the pathway, and amount of perturbation of downstream genes.

ISSN: 1471-2407