Table 2 The most differentially regulated genes in gastric tumor vs control mucosa
From: Up-regulation of CLDN1 in gastric cancer is correlated with reduced survival
Up-regulated genes (n=30) | Down-regulated genes (n=100) | ||||||
|---|---|---|---|---|---|---|---|
Gene symbol | Average FC | Gene symbol | Average FC | Gene symbol | Average FC | Gene symbol | Average FC |
IL-8 | 2.58 | PGA4 | -5.58 | MAL | -2.22 | AKR7A3 | -1.79 |
COL1A1 | 2.18 | GIF | -5.48 | SCNN1B | -2.22 | KIAA1324 | -1.79 |
CLDN1 | 2.14 | ATP4A | -5.28 | SOX21 | -2.22 | CCDC121 | -1.78 |
SPP1 | 2.09 | PGA3 | -4.72 | CAPN9 | -2.21 | FBP2 | -1.76 |
CLDN2 | 2.09 | ATP4B | -4.71 | AGXT2L1 | -2.20 | FCGBP | -1.75 |
CEACAM6 | 2.09 | PGA5 | -4.34 | HDC | -2.18 | ORM2 | -1.75 |
SERPINB5 | 2.06 | LIPF | -3.91 | GSTA1 | -2.18 | FAM3B | -1.73 |
KRT17 | 2.00 | CPA2 | -3.78 | KLK11 | -2.12 | TRIM50 | -1.73 |
H19 | 1.94 | GHRL | -3.75 | APLP1 | -2.12 | DUOX1 | -1.72 |
CLDN7 | 1.93 | GKN2 | -3.26 | MT1H | -2.09 | RAP1GAP | -1.70 |
TFF3 | 1.92 | KCNE2 | -3.19 | ADH1C | -2.09 | EEF1A2 | -1.70 |
OLFM4 | 1.91 | SST | -3.12 | DPCR1 | -2.06 | ANGPTL3 | -1.70 |
THBS2 | 1.91 | CHGA | -3.02 | AKR1B10 | -2.03 | B3GAT1 | -1.69 |
PI3 | 1.90 | PSCA | -3.00 | MT1G | -2.03 | C6ORF105 | -1.68 |
SULF1 | 1.89 | CHIA | -2.88 | CKB | -2.01 | FGG | -1.68 |
BGN | 1.82 | GKN1 | -2.88 | SH3GL2 | -1.99 | ADA | -1.65 |
KRT6B | 1.80 | KCNJ16 | -2.82 | REP15 | -1.97 | C6ORF58 | -1.63 |
THY1 | 1.72 | GC | -2.66 | CKM | -1.95 | ZNF533 | -1.60 |
MMP11 | 1.70 | CLIC6 | -2.65 | FGA | -1.95 | RPESP | -1.59 |
KLK6 | 1.67 | SOSTDC1 | -2.53 | SLC9A4 | -1.92 | MT1F | -1.58 |
SERPINA3 | 1.65 | ESRRG | -2.52 | MFSD4 | -1.92 | PNPLA7 | -1.57 |
FNDC1 | 1.64 | CCKBR | -2.51 | ALDOB | -1.89 | FUT9 | -1.57 |
COL1A2 | 1.63 | TMED6 | -2.44 | SCNN1G | -1.87 | RPRM | -1.56 |
CST1 | 1.63 | MT1M | -2.44 | IRX2 | -1.87 | GUCA2B | -1.56 |
FAP | 1.60 | GPER | -2.43 | SLC26A9 | -1.87 | TCN1 | -1.55 |
COL6A3 | 1.60 | CKMT2 | -2.36 | CLCNKA | -1.87 | PKIB | -1.55 |
SFRP4 | 1.56 | VSIG2 | -2.36 | CAPN13 | -1.86 | SLC9A2 | -1.55 |
TMEM158 | 1.53 | FLJ42875 | -2.33 | TTR | -1.86 | HOMER2 | -1.53 |
MMP7 | 1.50 | CXCL17 | -2.32 | GSTA2 | -1.85 | AKR1C4 | -1.50 |
MMP10 | 1.50 | CA9 | -2.32 | NKX6-2 | -1.83 | REG3A | -1.50 |
| Â | Â | AKR1C2 | -2.27 | CA2 | -1.83 | PI16 | -1.50 |
| Â | Â | ALDH3A1 | -2.24 | FOLR1 | -1.82 | MAP7D2 | -1.50 |
| Â | Â | SCGB2A1 | -2.23 | RDH12 | -1.81 | Â | Â |
| Â | Â | AQP4 | -2.24 | IRX3 | -1.80 | Â | Â |