Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients

BMC Cancer

Table 2 Overview of chromosomal aberrations in SCCs and AKs

	Type of aberration	Cytoband	Mb location	Size (Mb)
SCC_P-03	Loss	4q28.3	1:136,448,440 - 136,988,409	0.54	*
	Gain	5p			*
	Gain	14q23.1-32.2	14:57,558,740 - 96,468,442	38.9	*
SCC_P-11	Gain	9q			*
SCC_P-18	Gain	8q24.22-24.23	8:132,122,430 - 139,467,653	7.3	*
	Gain	14q13.3	14:71,054,120 - 73,596,540	2.5
	Gain	9p23-tel	9:1–12,039,121	12	*
	Loss	9p23-cen		~40	*
	Loss	9q			*
	Loss	14q13.3-tel		~70	*
	cnLOH	17			*
SCC_P-27	Loss	3p
	Gain	3q
	Loss	4p12-tel	4:1–46,377,946	46,4	*
	Gain	5q25.3-tel	5:83,159,010 - 100,338,915	17.1	*
	Loss	6q13-14.1	6:75,600,000 - 76,627,715	1.0	*
	Loss	9p
	Gain	9q
	cnLOH	18p
SCC_P-38	cnLOH	6p21.31-tel	6:1–35,593,684	35.5
	Loss	9p
	Loss	14q
SCC_P-41	cnLOH	22q12.1-tel	22:24,348,300 - 49,554,696	25.2
AK_P-03	Loss	4q			*
	Loss	5q15-31.1	5:96,745,240 - 133,072,806	36.3	*
	cnLOH	5q31.1-tel	5:133,268,490 - 180,857,816	47.2	*
	cnLOH	9q			*
AK_P-05	Loss	5q			*
	Loss	9p21.1-tel	9:1–33,109,143		*
AK_P-11	Loss	2p22.2-25.1	2:11,690,000 - 36,950,000	25.3	*
	cnLOH	8p			*
	Loss	13q			*
	Loss	17p			*
	Loss	18q12.1-tel	18:26,013,440 - 76,117,152	50.1	*
AK_P-33	Loss	6q22.31-tel	6:122,757,319 - 170,975,699	48.2	*
AK_P-41	Loss	1p32.3	1:54,783,720 - 55,100,840	0.4	*
	Loss	3p
	Gain	3q			*
	Loss	4q33-tel	4:171,450,620 - 191,411,215	20.0
	Gain	5q31.2-tel	5:138,387,890 - 180,857,851	42.5	*
	Loss	8p12-tel	8:1–38,377,990	38.4
	Loss	8q22.1	8:95,250,740 - 96,376,326	1.3
	Loss	9p22.2-cen	9:17,230,530 - 50,549,240	33.3
	Gain	10p	10:1–40,144,085	40.1	*
	Loss	12q24.23		0.5
	Loss	14q
AK_P-44	cnLOH	8q33.3-tel	8:126,444,040 - 137,979,818	11.4

* heterogeneous chromosomal aberration: observed in less than 70% of the tumor sample.

ISSN: 1471-2407