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Table 2 Overview of chromosomal aberrations in SCCs and AKs

From: Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients

  Type of aberration Cytoband Mb location Size (Mb)  
SCC_P-03 Loss 4q28.3 1:136,448,440 - 136,988,409 0.54 *
  Gain 5p    *
  Gain 14q23.1-32.2 14:57,558,740 - 96,468,442 38.9 *
SCC_P-11 Gain 9q    *
SCC_P-18 Gain 8q24.22-24.23 8:132,122,430 - 139,467,653 7.3 *
  Gain 14q13.3 14:71,054,120 - 73,596,540 2.5  
  Gain 9p23-tel 9:1–12,039,121 12 *
  Loss 9p23-cen   ~40 *
  Loss 9q    *
  Loss 14q13.3-tel   ~70 *
  cnLOH 17    *
SCC_P-27 Loss 3p    
  Gain 3q    
  Loss 4p12-tel 4:1–46,377,946 46,4 *
  Gain 5q25.3-tel 5:83,159,010 - 100,338,915 17.1 *
  Loss 6q13-14.1 6:75,600,000 - 76,627,715 1.0 *
  Loss 9p    
  Gain 9q    
  cnLOH 18p    
SCC_P-38 cnLOH 6p21.31-tel 6:1–35,593,684 35.5  
  Loss 9p    
  Loss 14q    
SCC_P-41 cnLOH 22q12.1-tel 22:24,348,300 - 49,554,696 25.2  
AK_P-03 Loss 4q    *
  Loss 5q15-31.1 5:96,745,240 - 133,072,806 36.3 *
  cnLOH 5q31.1-tel 5:133,268,490 - 180,857,816 47.2 *
  cnLOH 9q    *
AK_P-05 Loss 5q    *
  Loss 9p21.1-tel 9:1–33,109,143   *
AK_P-11 Loss 2p22.2-25.1 2:11,690,000 - 36,950,000 25.3 *
  cnLOH 8p    *
  Loss 13q    *
  Loss 17p    *
  Loss 18q12.1-tel 18:26,013,440 - 76,117,152 50.1 *
AK_P-33 Loss 6q22.31-tel 6:122,757,319 - 170,975,699 48.2 *
AK_P-41 Loss 1p32.3 1:54,783,720 - 55,100,840 0.4 *
  Loss 3p    
  Gain 3q    *
  Loss 4q33-tel 4:171,450,620 - 191,411,215 20.0  
  Gain 5q31.2-tel 5:138,387,890 - 180,857,851 42.5 *
  Loss 8p12-tel 8:1–38,377,990 38.4  
  Loss 8q22.1 8:95,250,740 - 96,376,326 1.3  
  Loss 9p22.2-cen 9:17,230,530 - 50,549,240 33.3  
  Gain 10p 10:1–40,144,085 40.1 *
  Loss 12q24.23   0.5  
  Loss 14q    
AK_P-44 cnLOH 8q33.3-tel 8:126,444,040 - 137,979,818 11.4  
  1. * heterogeneous chromosomal aberration: observed in less than 70% of the tumor sample.