Table 1 Patient and treatment characteristics
Characteristics | Value (%) |
|---|---|
Median age, years (range) | 56 (27–78) |
Gender | |
Male | 106 (70.2) |
Female | 45 (29.8) |
ECOG | |
0 | 40 (26.5) |
1 | 110 (72.8) |
2 | 1 (0.7) |
Clinical T stage | |
T1/T2 | 0 (0.0)/14 (9.3) |
T3/T4 | 126 (83.5)/11 (7.2) |
Clinical N stage | |
N (−) | 31 (20.5) |
N (+) | 120 (79.5) |
Distance from anal verge (cm) | |
≤ 5 cm | 120 (79.5) |
> 5 cm | 31 (20.5) |
Pretreatment CEA | |
Normal (≤ 5 ng/ml) | 107 (70.9) |
Elevated (> 5 ng/ml) | 44 (29.1) |
Median radiation dose, Gy (range) | 50.4 (50.4–55.8) |
Combined chemotherapy | |
5-fluorouracil | 133 (88.1) |
Capecitabine | 18 (11.9) |
Type of surgery | |
Low anterior resection | 139 (92.1) |
Abdominoperineal resection | 12 (7.9) |
Pathology | |
Adenocarcinoma | 143 (94.7) |
Mucinous carcinoma | 7 (4.6) |
Signet ring cell carcinoma | 1 (0.7) |
ypT stage | |
Tis/T1 | 3 (2.0)/10 (6.6) |
T2/T3 | 49 (32.5)/89 (58.9) |
ypN stage | |
N0 | 94 (62.3) |
N1 | 47 (31.1) |
N2 | 10 (6.6) |
Lymphatic invasion | |
Yes | 19 (12.6) |
No | 132 (87.4) |
Vascular invasion | |
Yes | 7 (4.6) |
No | 144 (95.4) |
Perineural invasion | |
Yes | 23 (15.2) |
No | 128 (84.8) |