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Figure 3 | BMC Cancer

Figure 3

From: The novel myxofibrosarcoma cell line MUG-Myx1 expresses a tumourigenic stem-like cell population with high aldehyde dehydrogenase 1 activity

Figure 3

Characterization of the ALDH1 high subpopulation. (A) Aldehyde dehydrogenase 1 (ALDH1) expression in MUG-Myx1 cells using the Aldefluor® assay. (B) ALDH1 expression in percentage of gated cells. (C) The normalized expression levels from ABC transporter genes and stemness markers in ALDH1high cells compared to ALDH1low control cells (black bar). (D) SCID mice ALDH1low and ALDH1high tumours differed significantly in their tumour weights. (E) The IHC analysis using anti-Ki-67 proliferation marker revealed an increased proliferation level of ALDH1high as compared to ALDH1low mouse tumours.

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