Survival of patients with primary breast cancers. Patient survival was assessed using the Kaplan-Meier method. Clinical breast cancer patients were followed for more than 120 months and classified into groups based on the expression of DSS1 mRNA, which was determined using qRT-PCR of total RNAs from 289 primary invasive breast cancer patients. (A) BCSS (left) and RFS (right) of the DSS1 low (n = 248) and high (n = 41) groups are shown. Statistical significance was calculated as log-rank: n.s.
P = 0.25 (left) and *P = 0.011 (right), respectively. (B) The patient survival was compared using double markers with p53 and DSS1 mRNAs as p53low/DSS1
low (n = 120), p53low/DSS1
high (n = 31), p53high/DSS1
low (n = 85), and p53high/DSS1
high (n = 10) groups. Statistical significance was calculated as log-rank: n.s.
P = 0.49 (left) and *P = 0.045 (right), respectively.