TY - JOUR AU - Balmain, A. AU - Gray, J. AU - Ponder, B. PY - 2003 DA - 2003// TI - The genetics and genomics of cancer JO - Nat Genet VL - 33 UR - https://doi.org/10.1038/ng1107 DO - 10.1038/ng1107 ID - Balmain2003 ER - TY - JOUR AU - Collins, N. AU - McManus, R. AU - Wooster, R. AU - Mangion, J. AU - Seal, S. AU - Lakhani, S. R. AU - Ormiston, W. AU - Daly, P. A. AU - Ford, D. AU - Easton, D. F. PY - 1995 DA - 1995// TI - Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13 JO - Oncogene VL - 10 ID - Collins1995 ER - TY - JOUR AU - Gudmundsson, J. AU - Johnnesdottir, G. AU - Bergthorsson, J. T. AU - Arason, A. AU - Ingvarsson, S. AU - Egilsson, V. AU - Barkardottir, R. B. PY - 1995 DA - 1995// TI - Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13 JO - Cancer Res VL - 55 ID - Gudmundsson1995 ER - TY - JOUR AU - Sharan, S. K. AU - Morimatsu, M. AU - Albrecht, U. AU - Lim, D. S. AU - Regel, E. AU - Dinh, C. AU - Sands, A. AU - Eichele, G. AU - Hasty, P. AU - Bradley, A. PY - 1997 DA - 1997// TI - Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 JO - Nature VL - 386 UR - https://doi.org/10.1038/386804a0 DO - 10.1038/386804a0 ID - Sharan1997 ER - TY - JOUR AU - Yuan, S. S. AU - Lee, S. Y. AU - Chen, G. AU - Song, M. AU - Tomlinson, G. E. AU - Lee, E. Y. PY - 1999 DA - 1999// TI - BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo JO - Cancer Res VL - 59 ID - Yuan1999 ER - TY - JOUR AU - Moynahan, M. E. AU - Cui, T. Y. AU - Jasin, M. PY - 2001 DA - 2001// TI - Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation JO - Cancer Res VL - 61 ID - Moynahan2001 ER - TY - JOUR AU - Lomonosov, M. AU - Anand, S. AU - Sangrithi, M. AU - Davies, R. AU - Venkitaraman, A. R. PY - 2003 DA - 2003// TI - Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein JO - Genes Dev VL - 17 UR - https://doi.org/10.1101/gad.279003 DO - 10.1101/gad.279003 ID - Lomonosov2003 ER - TY - JOUR AU - Godthelp, B. C. AU - Wiegant, W. W. AU - Waisfisz, Q. AU - Medhurst, A. L. AU - Arwert, F. AU - Joenje, H. AU - Zdzienicka, M. Z. PY - 2006 DA - 2006// TI - Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2 JO - Mutat Res VL - 594 UR - https://doi.org/10.1016/j.mrfmmm.2005.07.008 DO - 10.1016/j.mrfmmm.2005.07.008 ID - Godthelp2006 ER - TY - JOUR AU - Lee, S. A. AU - Baker, M. D. PY - 2007 DA - 2007// TI - Analysis of DNA repair and recombination responses in mouse cells depleted for Brca2 by SiRNA JO - DNA Repair (Amst) VL - 6 UR - https://doi.org/10.1016/j.dnarep.2007.01.007 DO - 10.1016/j.dnarep.2007.01.007 ID - Lee2007 ER - TY - JOUR AU - Struewing, J. P. AU - Hartge, P. AU - Wacholder, S. AU - Baker, S. M. AU - Berlin, M. AU - McAdams, M. AU - Timmerman, M. M. AU - Brody, L. C. AU - Tucker, M. A. PY - 1997 DA - 1997// TI - The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews JO - N Engl J Med VL - 336 UR - https://doi.org/10.1056/NEJM199705153362001 DO - 10.1056/NEJM199705153362001 ID - Struewing1997 ER - TY - JOUR AU - Bièche, I. AU - Noguès, C. AU - Lidereau, R. PY - 1999 DA - 1999// TI - Overexpression of BRCA2 gene in sporadic breast tumours JO - Oncogene VL - 18 UR - https://doi.org/10.1038/sj.onc.1202903 DO - 10.1038/sj.onc.1202903 ID - Bièche1999 ER - TY - JOUR AU - Venkitaraman, A. R. PY - 2002 DA - 2002// TI - Cancer susceptibility and the functions of BRCA1 and BRCA2 JO - Cell VL - 108 UR - https://doi.org/10.1016/S0092-8674(02)00615-3 DO - 10.1016/S0092-8674(02)00615-3 ID - Venkitaraman2002 ER - TY - JOUR AU - Egawa, C. AU - Miyoshi, Y. AU - Taguchi, T. AU - Tamaki, Y. AU - Noguchi, S. PY - 2002 DA - 2002// TI - High BRCA2 mRNA expression predicts poor prognosis in breast cancer patients JO - Int J Cancer VL - 98 UR - https://doi.org/10.1002/ijc.10231 DO - 10.1002/ijc.10231 ID - Egawa2002 ER - TY - JOUR AU - Bièche, I. AU - Tozlu, S. AU - Girault, I. AU - Lidereau, R. PY - 2004 DA - 2004// TI - Identification of a three-gene expression signature of poor-prognosis breast carcinoma JO - Mol Cancer VL - 3 UR - https://doi.org/10.1186/1476-4598-3-37 DO - 10.1186/1476-4598-3-37 ID - Bièche2004 ER - TY - JOUR AU - Magwood, A. C. AU - Mundia, M. M. AU - Baker, M. D. PY - 2012 DA - 2012// TI - High levels of wild-type BRCA2 suppress homologous recombination JO - J Mol Biol VL - 421 UR - https://doi.org/10.1016/j.jmb.2012.05.007 DO - 10.1016/j.jmb.2012.05.007 ID - Magwood2012 ER - TY - JOUR AU - Gudmundsdottir, K. AU - Lord, C. J. AU - Witt, E. AU - Tutt, A. N. AU - Ashworth, A. PY - 2004 DA - 2004// TI - DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells JO - EMBO Rep VL - 5 UR - https://doi.org/10.1038/sj.embor.7400255 DO - 10.1038/sj.embor.7400255 ID - Gudmundsdottir2004 ER - TY - JOUR AU - Wilmes, G. M. AU - Bergkessel, M. AU - Bandyopadhyay, S. AU - Shales, M. AU - Braberg, H. AU - Cagney, G. AU - Collins, S. R. AU - Whitworth, G. B. AU - Kress, T. L. AU - Weissman, J. S. AU - Ideker, T. AU - Guthrie, C. AU - Krogan, N. J. PY - 2008 DA - 2008// TI - A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing JO - Mol Cell VL - 32 UR - https://doi.org/10.1016/j.molcel.2008.11.012 DO - 10.1016/j.molcel.2008.11.012 ID - Wilmes2008 ER - TY - JOUR AU - Ohta, K. AU - Kuwahara, K. AU - Zhang, Z. AU - Makino, K. AU - Komohara, Y. AU - Nakamura, H. AU - Kuratsu, J. AU - Sakaguchi, N. PY - 2009 DA - 2009// TI - Decreased expression of germinal center-associated nuclear protein is involved in chromosomal instability in malignant gliomas JO - Cancer Sci VL - 100 UR - https://doi.org/10.1111/j.1349-7006.2009.01293.x DO - 10.1111/j.1349-7006.2009.01293.x ID - Ohta2009 ER - TY - JOUR AU - Nakaya, T. AU - Kuwahara, K. AU - Ohta, K. AU - Kitabatake, M. AU - Toda, T. AU - Takeda, N. AU - Tani, T. AU - Kondo, E. AU - Sakaguchi, N. PY - 2010 DA - 2010// TI - Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression JO - J Immunol VL - 185 UR - https://doi.org/10.4049/jimmunol.1002026 DO - 10.4049/jimmunol.1002026 ID - Nakaya2010 ER - TY - JOUR AU - Wei, S. J. AU - Williams, J. G. AU - Dang, H. AU - Darden, T. A. AU - Betz, B. L. AU - Humble, M. M. AU - Chang, F. M. AU - Trempus, C. S. AU - Johnson, K. AU - Cannon, R. E. AU - Tennant, R. W. PY - 2008 DA - 2008// TI - Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation JO - J Mol Biol VL - 383 UR - https://doi.org/10.1016/j.jmb.2008.08.044 DO - 10.1016/j.jmb.2008.08.044 ID - Wei2008 ER - TY - JOUR AU - Kim, H. S. AU - Yom, C. K. AU - Kim, H. J. AU - Lee, J. W. AU - Sohn, J. H. AU - Kim, J. H. AU - Park, Y. L. AU - Ahn, S. H. PY - 2010 DA - 2010// TI - Overexpression of p53 is correlated with poor outcome in premenopausal women with breast cancer treated with tamoxifen after chemotherapy JO - Breast Cancer Res Treat VL - 121 UR - https://doi.org/10.1007/s10549-009-0560-5 DO - 10.1007/s10549-009-0560-5 ID - Kim2010 ER - TY - JOUR AU - Pulyaeva, H. AU - Bueno, J. AU - Polette, M. AU - Birembaut, P. AU - Sato, H. AU - Seiki, M. AU - Thompson, E. W. PY - 1997 DA - 1997// TI - MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells JO - Clin Exp Metastasis VL - 15 UR - https://doi.org/10.1023/A:1018444609098 DO - 10.1023/A:1018444609098 ID - Pulyaeva1997 ER - TY - JOUR AU - Li, J. AU - Zou, C. AU - Bai, Y. AU - Wazer, D. E. AU - Band, V. AU - Gao, Q. PY - 2006 DA - 2006// TI - DSS1 is required for the stability of BRCA2 JO - Oncogene VL - 25 UR - https://doi.org/10.1038/sj.onc.1209153 DO - 10.1038/sj.onc.1209153 ID - Li2006 ER - TY - JOUR AU - Yang, G. AU - Mercado-Uribe, I. AU - Multani, A. S. AU - Sen, S. AU - Shih, I. M. AU - Wong, K. K. AU - Gershenson, D. M. AU - Liu, J. PY - 2013 DA - 2013// TI - RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis JO - Int J Cancer VL - 133 UR - https://doi.org/10.1002/ijc.28032 DO - 10.1002/ijc.28032 ID - Yang2013 ER - TY - JOUR AU - Ma, Y. Y. AU - Lin, H. AU - Chang, F. M. AU - Chang, T. C. AU - Trieu, T. AU - Pridgen, H. I. AU - Zhang, Y. AU - Huang, J. AU - Patiño-Guzman, K. AU - Diab, N. AU - Cantu, A. AU - Slaga, T. J. AU - Wei, S. J. PY - 2013 DA - 2013// TI - Identification of the deleted in split hand/split foot 1 protein as a novel biomarker for human cervical cancer JO - Carcinogenesis VL - 34 UR - https://doi.org/10.1093/carcin/bgs279 DO - 10.1093/carcin/bgs279 ID - Ma2013 ER - TY - JOUR AU - Roy, R. AU - Chun, J. AU - Powell, S. N. PY - 2012 DA - 2012// TI - BRCA1 and BRCA2: different roles in a common pathway of genome protection JO - Nat Rev Cancer VL - 12 UR - https://doi.org/10.1038/nrc3181 DO - 10.1038/nrc3181 ID - Roy2012 ER - TY - JOUR AU - Xia, F. AU - Taghian, D. G. AU - DeFrank, J. S. AU - Zeng, Z. C. AU - Willers, H. AU - Iliakis, G. AU - Powell, S. N. PY - 2001 DA - 2001// TI - Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining JO - Proc Natl Acad Sci USA VL - 98 UR - https://doi.org/10.1073/pnas.151253498 DO - 10.1073/pnas.151253498 ID - Xia2001 ER - TY - JOUR AU - Chapman, J. R. AU - Taylor, M. R. AU - Boulton, S. J. PY - 2012 DA - 2012// TI - Playing the end game: DNA double-strand break repair pathway choice JO - Mol Cell VL - 47 UR - https://doi.org/10.1016/j.molcel.2012.07.029 DO - 10.1016/j.molcel.2012.07.029 ID - Chapman2012 ER - TY - JOUR AU - Moynahan, M. E. AU - Jasin, M. PY - 2010 DA - 2010// TI - Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis JO - Nat Rev Mol Cell Biol VL - 11 UR - https://doi.org/10.1038/nrm2851 DO - 10.1038/nrm2851 ID - Moynahan2010 ER - TY - JOUR AU - Hanawalt, P. C. AU - Spivak, G. PY - 2008 DA - 2008// TI - Transcription-coupled DNA repair: two decades of progress and surprises JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2549 DO - 10.1038/nrm2549 ID - Hanawalt2008 ER - TY - JOUR AU - Negrini, S. AU - Gorgoulis, V. G. AU - Halazonetis, T. D. PY - 2010 DA - 2010// TI - Genomic instability–an evolving hallmark of cancer JO - Nat Rev Mol Cell Biol VL - 11 UR - https://doi.org/10.1038/nrm2858 DO - 10.1038/nrm2858 ID - Negrini2010 ER - TY - JOUR AU - Jani, D. AU - Lutz, S. AU - Hurt, E. AU - Laskey, R. A. AU - Stewart, M. AU - Wickramasinghe, V. O. PY - 2012 DA - 2012// TI - Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gks059 DO - 10.1093/nar/gks059 ID - Jani2012 ER - TY - JOUR AU - Wickramasinghe, V. O. AU - McMurtrie, P. I. AU - Mills, A. D. AU - Takei, Y. AU - Penrhyn-Lowe, S. AU - Amagase, Y. AU - Main, S. AU - Marr, J. AU - Stewart, M. AU - Laskey, R. A. PY - 2010 DA - 2010// TI - mRNA export from mammalian cell nuclei is dependent on GANP JO - Curr Biol VL - 20 UR - https://doi.org/10.1016/j.cub.2009.10.078 DO - 10.1016/j.cub.2009.10.078 ID - Wickramasinghe2010 ER - TY - JOUR AU - Sinha, B. K. AU - Haim, N. AU - Dusre, L. AU - Kerrigan, D. AU - Pommier, Y. PY - 1988 DA - 1988// TI - DNA strand breaks produced by etoposide (VP-16,213) in sensitive and resistant human breast tumor cells: implications for the mechanism of action JO - Cancer Res VL - 48 ID - Sinha1988 ER - TY - JOUR AU - Liu, Y. Y. AU - Yu, J. Y. AU - Yin, D. AU - Patwardhan, G. A. AU - Gupta, V. AU - Hirabayashi, Y. AU - Holleran, W. M. AU - Giuliano, A. E. AU - Jazwinski, S. M. AU - Gouaze-Andersson, V. AU - Consoli, D. P. AU - Cabot, M. C. PY - 2008 DA - 2008// TI - A role for ceramide in driving cancer cell resistance to doxorubicin JO - FASEB J VL - 22 UR - https://doi.org/10.1096/fj.07-092981 DO - 10.1096/fj.07-092981 ID - Liu2008 ER - TY - JOUR AU - Pegg, A. E. PY - 1990 DA - 1990// TI - Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents JO - Cancer Res VL - 50 ID - Pegg1990 ER - TY - JOUR AU - Lage, H. AU - Dietel, M. PY - 1999 DA - 1999// TI - Involvement of the DNA mismatch repair system in antineoplastic drug resistance JO - J Cancer Res Clin Oncol VL - 125 UR - https://doi.org/10.1007/s004320050258 DO - 10.1007/s004320050258 ID - Lage1999 ER - TY - JOUR AU - Lage, H. AU - Dietel, M. PY - 2000 DA - 2000// TI - Effect of the breast-cancer resistance protein on atypical multidrug resistance JO - Lancet Oncol VL - 1 UR - https://doi.org/10.1016/S1470-2045(00)00032-2 DO - 10.1016/S1470-2045(00)00032-2 ID - Lage2000 ER - TY - JOUR AU - Egawa, C. AU - Miyoshi, Y. AU - Takamura, Y. AU - Taguchi, T. AU - Tamaki, Y. AU - Noguchi, S. PY - 2001 DA - 2001// TI - Decreased expression of BRCA2 mRNA predicts favorable response to docetaxel in breast cancer JO - Int J Cancer VL - 95 UR - https://doi.org/3.0.CO;2-O DO - 3.0.CO;2-O ID - Egawa2001 ER - TY - JOUR AU - Rytelewski, M. AU - Ferguson, P. J. AU - Maleki Vareki, S. AU - Figueredo, R. AU - Vincent, M. AU - Koropatnick, J. PY - 2013 DA - 2013// TI - Inhibition of BRCA2 and thymidylate synthase creates multidrug sensitive tumor cells via the induction of combined "complementary lethality" JO - Mol Ther Nucleic Acids VL - 2 UR - https://doi.org/10.1038/mtna.2013.7 DO - 10.1038/mtna.2013.7 ID - Rytelewski2013 ER - TY - STD TI - The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2407/13/562/prepub UR - http://www.biomedcentral.com/1471-2407/13/562/prepub ID - ref41 ER -