Skip to main content

Table 3 Risks of oral cavity cancer associated with family history of cancer among first-degree relatives

From: Family history of cancer, personal history of medical conditions and risk of oral cavity cancer in France: the ICARE study

  Cases N Controls N OR (95% CI)†, ‡
Family history of cancer (father)    
All type of cancer    
Never 430 2503 1 (reference)
Ever 185 796 1.3 (0.9-1.6)
Head and neck cancer    
Never 576 3200 1 (reference)
Ever 39 99 1.5 (0.9-2.4)
Family history of cancer (mother)    
All type of cancer    
Never 543 2784 1 (reference)
Ever 97 603 0.9 (0.6-1.2)
Head and neck cancer    
Never 633 3378 1 (reference)
Ever 7 9 5.2 (1.2-23.9)
Family history of cancer (brothers)    
All type of cancer    
Never 229 1218 1 (reference)
Ever 77 288 1.4 (0.9-2.1)
Head and neck cancer    
Never 286 1467 1 (reference)
Ever 20 39 2.6 (1.2-5.8)
Family history of cancer (sisters)    
All type of cancer    
Never 190 1236 1 (reference)
Ever 72 309 1.4 (0.9-2.1)
Head and neck cancer    
Never 251 1517 1 (reference)
Ever 11 28 1.7 (0.6-4.2)
Family history of cancer (any first-degree relative)   
All type of cancer    
Never 250 1567 1 (reference)
Ever 333 1595 1.2 (0.9-1.5)
1-2 329 1552 1.0 (0.8-1.3)
≥3 4 43 1.5 (1.0-2.1)
Head and neck cancer    
Never 462 2784 1 (reference)
Ever 68 157 1.9 (1.2-2.8)
1-2 64 150 1.7 (1.1-2.6)
≥3 4 7 7.2 (1.3-40.1)
  1. OR adjusted for age, gender, area of residence, education level, tobacco smoking (duration, quantity and status), alcohol drinking (quantity) and BMI two years before the interview.
  2. OR adjusted, in addition to the variables of the first model, for the number of brothers, sisters or siblings, respectively.