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Table 3 *ORs for the associations between UGT2B15 and UGT2B17 SNPs and PC

From: Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study

SNP # Allele Cases n (%) Controls n (%) OR (95% CI)*
UGT2B15    
rs1580083    
TT 2 (0.86) 5 (1.47) Reference
TA 150 (64.38) 249 (73.45) 2.32 (0.23-23.81)
AA 81 (34.76) 85 (25.07) 3.24 (0.31-33.93)
AA/TA 231 (99.14) 334 (98.52) 2.54 (0.25-26.00)
Log additive    1.43 (0.91-2.26)
rs1960773    
TT 1 (0.43) 5 (1.47) Reference
GT 144 (62.61) 244 (71.98) --
GG 85 (36.96) 90 (26.55) --
TT/GT 229 (99.56) 334 (98.52) --
Log additive    --
rs9994887    
AA 38 (16.31) 91 (26.84) Reference
AG 108 (46.35) 158 (46.61) 1.94 (1.06-3.53)
GG 87 (37.34) 90 (26.55) 2.38 (1.24-4.55)
GG/AG 195 (83.69) 248 (73.15) 2.10 (1.18-3.71)
Log additive    1.49 (1.09-2.04)
rs13112099    
TT 38 (16.31) 91 (26.61) Reference
GT 110 (47.21) 163 (47.66) 1.93 (1.06-3.52)
GG 85 (36.48) 88 (25.73) 2.35 (1.22-4.51)
GG/GT 195 (83.69) 251 (73.39) 2.07 (1.12-3.67)
Log additive    1.48 (1.08-2.03)
rs7686914    
TT 38 (16.45) 91 (26.84) Reference
CT 109 (47.19) 160 (47.20) 1.94 (1.06-3.55)
CC 84 (36.36) 88 (25.96) 2.34 (1.22-4.50)
CC/CT 193 (83.55) 248 (73.81) 2.10 (1.17-3.70)
Log additive    1.48 (1.08-2.03)
rs7696472    
GG 38 (16.31) 92 (26.97) Reference
AG 110 (47.21) 157 (46.04) 2.00 (1.10-3.63)
AA 85 (36.48) 90 (26.39) 2.30 (1.20-4.40)
AA/AG 195 (83.69) 249 (73.02) 2.10 (1.18-3.72)
Log additive    1.49 (1.06-2.00)
rs4148269    
CC 43 (18.45) 79 (23.23) Reference
CA 72 (30.90) 160 (47.05) 0.81 (0.45-1.46)
AA 115 (49.35) 101 (29.70) 1.98 (1.02-3.85)
AA/CA 190 (81.54) 261 (76.76) 1.10 (0.63-1.90)
Log additive    1.45 (1.03-2.03)
rs3100    
TT 54 (23.78) 106 (31.08) Reference
TC 68 (29.95) 140 (41.05) 1.04 (0.60-1.81)
CC 105 (46.25) 95 (27.85) 2.18 (1.19-3.99)
CC/TC 173 (76.21) 235 (68.91) 1.41 (0.86-2.31)
Log additive    1.46 (1.08-1.98)
Cis acting on UGT2B expression    
rs2168047    
AA 53 (22.84) 59 (17.45) Reference
GA 112 (48.27) 169 (50.00) 0.86 (0.48-1.53)
GG 67 (28.87) 110 (32.54) 1.00 (0.52-1.88)
GG/GA 179 (77.15) 279 (82.54) 0.90 (0.52-1.57)
Log additive    1.01 (0.74-1.38)
rs6822259    
CC 3 (1.29) 12 (3.52) Reference
CT 58 (25.00) 97 (28.44) 1.48 (0.36-6.02)
TT 171 (73.70) 232 (68.03) 1.34 (0.34-5.31)
TT/CT 229 (98.70) 329 (96.48) 1.39 (0.35-5.43)
Log additive    1.02 (0.68-1.53)
rs17147338    
CC 168 (72.1) 285 (83.58) Reference
CT 55 (23.61) 51 (14.96) 1.68 (0.96-2.97)
TT 10 (4.29) 5 (1.47) 2.41 (0.42-13.94)
TT/CT 65 (27.9) 56 (16.42) 1.73 (1.00-3.00)
Log additive    1.65 (1.00-2.70)
UGT2B17    
rs7435827    
GG 53 (24.20) 106 (32.61) Reference
GA 43 (19.63) 78 (24.00) 0.67 (0.35-1.30)
AA 123 (56.16) 141 (43.38) 0.90 (0.49-1.66)
AA/GA 166 (75.79) 219 (67.38) 0.80 (0.46-1.38)
Log additive    0.97 (0.71-1.36)
rs7686008    
AA 168 (71.79) 281 (82.4) Reference
AT 34 (14.53) 32 (9.38) 1.40 (0.69-2.79)
TT 32 (13.68) 28 (8.21) 1.40 (0.66-2.96)
TT/AT 66 (28.21) 60 (17.6) 1.39 (0.79-2.44)
Log additive    1.21 (0.85-1.73)
rs7671342    
GG 37 (15.94) 56 (16.37) Reference
GA 46 (19.83) 85 (24.85) 0.86 (0.43-1.73)
AA 149 (64.22) 201 (58.77) 1.32 (0.73-2.40)
AA/GA 195 (84.05) 286 (83.62) 1.17 (0.65-2.08)
Log additive    1.21 (0.91-1.61)
rs59678213    
CC 42 (19.44) 81 (25.63) Reference
TC 46 (21.29) 74 (23.42) 0.84 (0.43-1.63)
TT 128 (59.26) 161 (50.94) 0.85 (0.45-1.59)
TT/TC 174 (80.55) 235 (74.37) 0.84 (0.47-1.50)
Log additive    0.92 (0.68-1.26)
  1. *Adjusted for age, race and BMI.