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Table 1 UGT2B15 and UGT2B17 genotyped SNPs and Minor alleles

From: Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study

SNP

Function class

Minor allele/MAF

Reference

All

Afr. American

Caucasian

UGT2B15 SNPs

    

rs1580083

Promoter

T/0.74

0.70

0.80

34

rs1960773

Promoter (Nrf2)

T/0.73

0.70

0.76

34

rs9994887

Promoter

A/0.73

0.67

0.78

34

rs13112099

Promoter

T/0.74

0.70

0.78

34

rs7686914

Promoter

T/0.73

0.68

0.78

34

rs7696472

Promoter

G/0.73

0.68

0.76

34

rs4148269

Nonsyn (T523K)

C/0.70

0.70

0.85

36

rs3100

3′UTR

T/0.72

0.53

0.85

36

UGT2B17 SNPs

    

rs59678213

Promoter (FoxA1)

C/0.32

0.24

0.67

37

rs7435827

Intron

G/0.60

0.30

0.76

GVS

rs7686008

Intron

T/0.18

0.34

0.06

GVS

rs7671342

Intron

G/0.41

0.41

0.41

GVS

Cis acting on UGT2B expression

    

rs6822259^

Intergenic

C/0.32

0.30

0.30

38

rs17147338^^

Intergenic

T/0.16

0.30

0.079

38

rs2168047^^

Distal promoter

A/0.67

0.73

0.63

38

  1. ^cis-acting on UGT2B17 expression (36).
  2. ^^cis-acting on UGT2B17 and UGT2B15 expression (36).
  3. GVS – genome variation server.