SNP | Function class | Minor allele/MAF | Reference | ||
---|---|---|---|---|---|
All | Afr. American | Caucasian | |||
UGT2B15 SNPs | Â | Â | Â | Â | |
rs1580083 | Promoter | T/0.74 | 0.70 | 0.80 | 34 |
rs1960773 | Promoter (Nrf2) | T/0.73 | 0.70 | 0.76 | 34 |
rs9994887 | Promoter | A/0.73 | 0.67 | 0.78 | 34 |
rs13112099 | Promoter | T/0.74 | 0.70 | 0.78 | 34 |
rs7686914 | Promoter | T/0.73 | 0.68 | 0.78 | 34 |
rs7696472 | Promoter | G/0.73 | 0.68 | 0.76 | 34 |
rs4148269 | Nonsyn (T523K) | C/0.70 | 0.70 | 0.85 | 36 |
rs3100 | 3′UTR | T/0.72 | 0.53 | 0.85 | 36 |
UGT2B17 SNPs | Â | Â | Â | Â | |
rs59678213 | Promoter (FoxA1) | C/0.32 | 0.24 | 0.67 | 37 |
rs7435827 | Intron | G/0.60 | 0.30 | 0.76 | GVS |
rs7686008 | Intron | T/0.18 | 0.34 | 0.06 | GVS |
rs7671342 | Intron | G/0.41 | 0.41 | 0.41 | GVS |
Cis acting on UGT2B expression | Â | Â | Â | Â | |
rs6822259^ | Intergenic | C/0.32 | 0.30 | 0.30 | 38 |
rs17147338^^ | Intergenic | T/0.16 | 0.30 | 0.079 | 38 |
rs2168047^^ | Distal promoter | A/0.67 | 0.73 | 0.63 | 38 |