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Table 1 Correlation between GAD1 expression and clinical classification in OSCC

From: Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation

Clinical classification Total Result of immunostaining Pvalue
    No. of patients (%)  
    GAD1 (high) GAD1 (low)  
Age at surgery     
  < 60 17 15 (88%) 2 (12%) 0.527
   60 63 52 (83%) 11 (17%)  
Gender     
  Male 34 29 (85%) 5 (15%) 0.401
  Female 46 38 (83%) 8 (17%)  
T-primary tumor size     
  T1 8 6 (75%) 2 (25%) 0.263
  T2 48 38 (79%) 10 (21%)  
  T3 14 13 (93%) 1 (7%)  
  T4 10 10 (100%) 0 (0%)  
N-regional lymph node     
  N (negative) 48 36 (75%) 12 (25%) 0.011*
  N (positive) 32 31 (97%) 1 (3%)  
Stage     
  I 8 6 (75%) 2 (25%) 0.075
  II 40 30 (75%) 10 (25%)  
  III 20 19 (95%) 1 (5%)  
  IV 12 12 (100%) 0 (0%)  
Histopathlogical type     
  Well 54 46 (85%) 8 (15%) 0.441
  Moderately 16 14 (88%) 2 (12%)  
  Poorly 10 7 (70%) 3 (30%)  
Tumor site     
  Gingiva 20 18 (90%) 2 (10%) 0.243
  Tongue 52 44 (85%) 8 (15%)  
  Buccal mucosa 4 2 (50%) 2 (50%)  
  Oral floor 4 3 (75%) 1 (25%)  
  1. GAD1(high), up-regulated GAD1; GAD1 (low), down-regulated GAD1; * P < 0.05.