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Table 1 Correlation between GAD1 expression and clinical classification in OSCC

From: Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation

Clinical classification

Total

Result of immunostaining

Pvalue

   

No. of patients (%)

 
   

GAD1 (high)

GAD1 (low)

 

Age at surgery

    
 

< 60

17

15 (88%)

2 (12%)

0.527

 

 60

63

52 (83%)

11 (17%)

 

Gender

    
 

Male

34

29 (85%)

5 (15%)

0.401

 

Female

46

38 (83%)

8 (17%)

 

T-primary tumor size

    
 

T1

8

6 (75%)

2 (25%)

0.263

 

T2

48

38 (79%)

10 (21%)

 
 

T3

14

13 (93%)

1 (7%)

 
 

T4

10

10 (100%)

0 (0%)

 

N-regional lymph node

    
 

N (negative)

48

36 (75%)

12 (25%)

0.011*

 

N (positive)

32

31 (97%)

1 (3%)

 

Stage

    
 

I

8

6 (75%)

2 (25%)

0.075

 

II

40

30 (75%)

10 (25%)

 
 

III

20

19 (95%)

1 (5%)

 
 

IV

12

12 (100%)

0 (0%)

 

Histopathlogical type

    
 

Well

54

46 (85%)

8 (15%)

0.441

 

Moderately

16

14 (88%)

2 (12%)

 
 

Poorly

10

7 (70%)

3 (30%)

 

Tumor site

    
 

Gingiva

20

18 (90%)

2 (10%)

0.243

 

Tongue

52

44 (85%)

8 (15%)

 
 

Buccal mucosa

4

2 (50%)

2 (50%)

 
 

Oral floor

4

3 (75%)

1 (25%)

 
  1. GAD1(high), up-regulated GAD1; GAD1 (low), down-regulated GAD1; * P < 0.05.