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Table 3 Comparison of each US feature of 1449 thyroid nodules according to underlying echogenicity

From: Heterogeneous echogenicity of the underlying thyroid parenchyma: how does this affect the analysis of a thyroid nodule?

  Total Malignant Benign
  Heterogeneous echogenicity Homogeneous echogenicity P-value Heterogeneous echogenicity Homogeneous echogenicity P-value Heterogeneous echogenicity Homogeneous echogenicity P-value
Total number 317 1132   68 257   249 875  
Echogenicity    0.078    0.174    0.068
  Hyper/isoechogenicity 125 (39.4) 525 (46.4)   3 (4.4) 28 (10.9)   122 (49.0) 497 (56.8)  
  Hypoechogenicity 176 (55.5) 549 (48.5)   56 (82.4) 186 (72.4)   120 (48.2) 363 (41.5)  
  Marked hypoechogenicity 16 (5.1) 58 (5.1)   9 (13.2) 43 (16.7)   7 (2.8) 15 (1.7)  
Margin    0.005    0.314    <0.001
  Well circumscribed 203 (64.0) 818 (72.3)   12 (17.7) 60 (23.4)   191 (76.7) 758 (86.6)  
  microlobulated or irregular 114 (36.0) 314 (27.7)   56 (82.4) 197 (76.7)   58 (23.3) 117 (13.4)  
Calcifications    0.849    0.986    0.555
  Microcalcifications 42 (13.3) 141 (12.5)   29 (42.7) 108 (42.0)   13 (5.2) 33 (3.8)  
  Macrocalcifications 39 (12.3) 151 (13.3)   9 (13.2) 36 (14.0)   30 (12.1) 115 (13.1)  
  No calcifications 236 (74.5) 840 (74.2)   30 (44.1) 113 (44.0)   206 (82.7) 727 (83.1)  
Shape    0.737    0.790    0.245
  Wider than tall 251 (79.2) 906 (80.0)   29 (42.7) 105 (40.9)   222 (89.2) 801 (91.5)  
  Taller than wide 66 (20.8) 226 (20.0)   39 (57.4) 152 (59.1)   27 (10.8) 74 (8.5)