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Table 3 Comparison of each US feature of 1449 thyroid nodules according to underlying echogenicity

From: Heterogeneous echogenicity of the underlying thyroid parenchyma: how does this affect the analysis of a thyroid nodule?

 

Total

Malignant

Benign

 

Heterogeneous echogenicity

Homogeneous echogenicity

P-value

Heterogeneous echogenicity

Homogeneous echogenicity

P-value

Heterogeneous echogenicity

Homogeneous echogenicity

P-value

Total number

317

1132

 

68

257

 

249

875

 

Echogenicity

  

0.078

  

0.174

  

0.068

  Hyper/isoechogenicity

125 (39.4)

525 (46.4)

 

3 (4.4)

28 (10.9)

 

122 (49.0)

497 (56.8)

 

  Hypoechogenicity

176 (55.5)

549 (48.5)

 

56 (82.4)

186 (72.4)

 

120 (48.2)

363 (41.5)

 

  Marked hypoechogenicity

16 (5.1)

58 (5.1)

 

9 (13.2)

43 (16.7)

 

7 (2.8)

15 (1.7)

 

Margin

  

0.005

  

0.314

  

<0.001

  Well circumscribed

203 (64.0)

818 (72.3)

 

12 (17.7)

60 (23.4)

 

191 (76.7)

758 (86.6)

 

  microlobulated or irregular

114 (36.0)

314 (27.7)

 

56 (82.4)

197 (76.7)

 

58 (23.3)

117 (13.4)

 

Calcifications

  

0.849

  

0.986

  

0.555

  Microcalcifications

42 (13.3)

141 (12.5)

 

29 (42.7)

108 (42.0)

 

13 (5.2)

33 (3.8)

 

  Macrocalcifications

39 (12.3)

151 (13.3)

 

9 (13.2)

36 (14.0)

 

30 (12.1)

115 (13.1)

 

  No calcifications

236 (74.5)

840 (74.2)

 

30 (44.1)

113 (44.0)

 

206 (82.7)

727 (83.1)

 

Shape

  

0.737

  

0.790

  

0.245

  Wider than tall

251 (79.2)

906 (80.0)

 

29 (42.7)

105 (40.9)

 

222 (89.2)

801 (91.5)

 

  Taller than wide

66 (20.8)

226 (20.0)

 

39 (57.4)

152 (59.1)

 

27 (10.8)

74 (8.5)

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