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Table 1 RRM1 and RRM2B status in 251 FISH assessable primary tumor samples from advanced breast cancer patients

From: Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine

   RRM1   
RRM2B Deletion Normal Amplification Total
Deletion 3 5 0 8 (3.2%)
Normal 31 184 2 217 (86.4%)
Amplification 4 22 0 26 (10.4%)
  38 (15.1%) 211 (84.1%) 2 (0.8%) 251
  1. Abbreviations: FISH fluorescence in situ hybridization, RRM1 ribonucleotide reductase M1 subunit, RRM2B ribonucleotide reductase M2B subunit.