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Table 1 RRM1 and RRM2B status in 251 FISH assessable primary tumor samples from advanced breast cancer patients

From: Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine

  

RRM1

  

RRM2B

Deletion

Normal

Amplification

Total

Deletion

3

5

0

8 (3.2%)

Normal

31

184

2

217 (86.4%)

Amplification

4

22

0

26 (10.4%)

 

38 (15.1%)

211 (84.1%)

2 (0.8%)

251

  1. Abbreviations: FISH fluorescence in situ hybridization, RRM1 ribonucleotide reductase M1 subunit, RRM2B ribonucleotide reductase M2B subunit.