Figure 2From: Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine Distribution of FISH ratios in the 251 FISH assessable primary breast tumor samples. (A) Distribution of RRM1/CEN-11 ratios and (B) distribution of RRM2B/CEN-8 ratios. Abbreviation: CEN-8, centromere of chromosome 8; CEN-11, centromere of chromosome 11; FISH, fluorescence in situ hybridization; RRM1, ribonucleotide reductase M1 subunit; RRM2B, ribonucleotide reductase M2B subunit.Back to article page