Table 2 Univariate survival analysis of clinicopathological parameters and OPN

Gender

0.67

0.48

Female

Male

0.9

0.6–1.5

1.2

0.7–1.9

Age

0.81

0.05

< 65 years

> 65 years

1.1

0.6–1.7

1.6

1.0–2.7

Histology

0.91

0.08

Adenocarcinoma (incl.BAC)

Squamous cell carcinoma

1.0

0.6–1.8

1.7

1.0–2.9

Large cell carcinoma

1.2

0.6–2.4

1.6

0.8–3.1

pTNM

0.28

0.97

I

II

1.2

0.7–2.2

1.0

0.5–1.8

III

1.4

0.7–2.7

1.0

0.5–2.1

pT

0.26

0.74

pT1

pT2

1.1

0.6–2.0

1.3

0.8–2.3

pT3

1.4

0.6–3.4

0.9

0.3–2.4

pT4

1.8

0.6–5.2

1.2

0.4–4.2

pN

0.18

0.27

pN0

pN1–2

1.4

0.8–2.4

1.3

0.8–2.2

Tumor size

0.04

0.04

≤ 3.0 cm

≥ 3.1 cm

1.7

1.0–2.7

1.6

1.0–2.6

Differentiation

0.03

0.01

G1 (well)

G2 (moderate)

2.4

0.7–7–6

2.5

0.8–8.0

G3 (poor)

3.5

1.0–11.9

3.9

1.2–13.4

Osteopontin

0.005

0.04

0

1

2.0

0.9–4.5

1.2

0.6–2.4

2

3.9

1.5–10.4

2.7

1.2–6.3