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Table 2 Univariate survival analysis of clinicopathological parameters and OPN

From: Osteopontin is a prognostic biomarker in non-small cell lung cancer

  Relapse free survival Overall survival
Parameter p* HR 95% CI p* HR 95% CI
Gender 0.67    0.48   
Female       
Male   0.9 0.6–1.5   1.2 0.7–1.9
Age 0.81    0.05   
< 65 years       
> 65 years   1.1 0.6–1.7   1.6 1.0–2.7
Histology 0.91    0.08   
Adenocarcinoma (incl.BAC)       
Squamous cell carcinoma   1.0 0.6–1.8   1.7 1.0–2.9
Large cell carcinoma   1.2 0.6–2.4   1.6 0.8–3.1
pTNM 0.28    0.97   
I       
II   1.2 0.7–2.2   1.0 0.5–1.8
III   1.4 0.7–2.7   1.0 0.5–2.1
pT 0.26    0.74   
pT1       
pT2   1.1 0.6–2.0   1.3 0.8–2.3
pT3   1.4 0.6–3.4   0.9 0.3–2.4
pT4   1.8 0.6–5.2   1.2 0.4–4.2
pN 0.18    0.27   
pN0       
pN1–2   1.4 0.8–2.4   1.3 0.8–2.2
Tumor size 0.04    0.04   
≤ 3.0 cm       
≥ 3.1 cm   1.7 1.0–2.7   1.6 1.0–2.6
Differentiation 0.03    0.01   
G1 (well)       
G2 (moderate)   2.4 0.7–7–6   2.5 0.8–8.0
G3 (poor)   3.5 1.0–11.9   3.9 1.2–13.4
Osteopontin 0.005    0.04   
0       
1   2.0 0.9–4.5   1.2 0.6–2.4
2   3.9 1.5–10.4   2.7 1.2–6.3
  1. *p-values calculated by log rank test.