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Table 3 Rates of HBV screening a by screening period

From: Trends in hepatitis B virus screening at the onset of chemotherapy in a large US cancer center

Characteristic

Period 1b

Period 2c

Period 3d

P valuee

All patients

Screened patients

All patients

Screened patients

All patients

Screened patients

 

(N = 11,833)

(N = 1754)

(N = 5703)

(N = 1037)

(N = 1152)

(N = 229)

Age, years, mean (SD)

54.8 (13.6)

51.6 (15.6)

55.1 (13.4)

53.1 (15.2)

56.4 (13.1)

56.1 (14.7)

0.0001

Sex, no. (%)

       

 Female

6702

731 (10.9)

3263

464 (14.2) 14.22

643

110 (17.1) 17.11

<0.0001

 Male

5131

1023 (20.0) 19.94

2440

573 (23.5) 23.48

509

119 (23.4) 23.38

0.0003

Race/ethnicity, no. (%)

       

 White

8464

1269 (15.0)

3895

738 (19.0)

809

161 (19.9)

<0.0001

 Hispanic

1441

218 (15.1)

747

152 (20.4)

131

32 (24.0)

<0.0001

 Black

1301

143 (11.0)

654

83 (12.7)

137

21 (15.3)

0.04

 Asian

311

45 (14.5)

158

23 (14.6)

39

8 (19.4)

0.23

 Other

316

79 (25.0)

249

41(16.5)

36

7 (20.5)

0.02

US residence, no. (%)

11,480

1675 (14.6)

5499

997 (18.1)

1111

224 (20.0)

<0.0001

HBV risk factor, no. (%)

3412

572 (16.8)

1668

356 (21.3)

311

88 (28.3)

<0.0001

Cancer type, no. (%)

      

<0.0001

 Solid tumorf

9521

326 (3.4)

4602

208 (4.5)

908

47 (5.2)

<0.0001

 Hematologic malignancy

2312

1428 (61.8)

1101

829 (75.3)

244

182 (74.6)

<0.0001

Chemotherapy

       

Type, n (%)

 Rituximab

1244

785 (63.1)

606

481 (79.4)

127

94 (74.0)

<0.0001

 Non-rituximab

10,589

969 (9.4)

5097

556 (10.9)

1025

135 (13.2)

<0.0001

  1. Abbreviations: HBV hepatitis B virus, SD standard deviation, US United States.
  2. aHBV screening means that both hepatitis B surface antigen (HBsAg) test and antibody to hepatitis B core antigen (anti-HBc) test were ordered.
  3. bFirst chemotherapy administration from 1/1/04 through 12/18/2008.
  4. cFirst chemotherapy administration from 12/19/2008 through 9/30/2010.
  5. dFirst chemotherapy administration from 10/1/2010 through 4/30/11.
  6. eCochran-Armitage trend test compares screened patients vs. unscreened patients, over the 3 time periods.
  7. fExcludes primary liver cancer.