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Table 1 Patient’s characteristics

From: Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma

Type of surgery OLT PR Cohort A Cohort B
all PR for survival analysis
n = 157 82 (52%) 75 (48%) 157 49
Median age    57.6 64.1
Male 68 (83%) 63 (84%) 131 (83%) 42 (86%)
Female 14 (17%) 12 (16%) 26 (17%) 7 (14%)
Cirrhosis (histologically confirmed) 70 (85%) 41 (55%) 111 (71%) 24 (49%)
Etiology:
     - Alcohol-induced liver disease 29 (35.4%) 13 (17.3%) 42 (27%) 8 (16%)
     - Viral disease 38 (46%) 19 (25%) 63 (40%) 9 (18%)
         HBV 15 (18.3%) 9 (12%) 24 (15.2%) 5 (10%)
         HCV 26 (31.7) 7 (9.3%) 33 (21%) 5 (10%)
         HBV + HCV 3 (3.7%) 3 (4%) 6 (3.8) 1 (2%)
     - Others (cryptogenic, hemochromatosis, AIH, PBC) 9 (11%) 43 (57%) 52 (33%) 21 (43%)
TNM
pT1 11 (13%) 13 (17%) 24 (15%) 10 (20%)
pT2 30 (37%) 34 (45%) 64 (41%) 23 (47%)
pT3 11 (13%) 17 (23%) 28 (18%) 9 (18%)
pT4 17 (21%) 5 (7%) 22 (14%) 3 (6%)
pTx 13 (16%) 6 (8%) 19 (12%) 4 (8%)
pN0 40 (49%) 27 (36%) 67 (43%) 20 (41%)
pNx 40 (49%) 47 (63%) 87 (55%) 28 (57%)
pN1 2 (2%) 1 (1%) 3 (2%) 1 (2%)
pM0/Mx 80 (98%) 72 (96%) 152 (97%) 48 (98%)
pM1 2 (2%) 3 (4%) 5 (3%) 1 (2%)
Grading
G1 9 (11%) 6 (8%) 15 (10%) 6 (12%)
G2 45 (55%) 42 (56%) 87 (55%) 27 (55%)
G3 28 (34%) 26 (35%) 54 (34%) 16 (33%)
G4 - 1 (1%) 1 (1%) -