Annexin A7 suppresses lymph node metastasis of hepatocarcinoma cells in a mouse model

BMC Cancer

Table 2 Annexin A7 protein expression in primary and lymph node metastasized tumors

Tissue	N	Annexin A7 expression				p-value 1	p-value 2
Tissue	N	-	+	++	+++	p-value 1	p-value 2
F_{ANXA7-control} primary tumor	13	0	2	5	6	0.000^*	0.001^◆
lymph node metastasized tumor	16	10	1	4	1
F_ANXA7-down primary tumor	34	8	22	3	1		0.000^■
lymph node metastasized tumor	66	15	8	17	26	0.002^#
P_{ANXA7-control} primary tumor	11	5	5	1	0	0.000^Δ	0.001^●
Lymph node metastasized tumor	4	0	0	1	3
P_ANXA7-up primary tumor	26	1	5	7	13

P-value 1 shows the difference among different groups. *The expression of Annexin A7 in primary tumors of F_ANXA7-down cells vs. that of F_{ANXA7-control} cells. Δ The expression of Annexin A7 in primary tumors of P_ANXA7-up cells vs. that of P_{ANXA7-control} cells. # The expression of Annexin A7 in lymph node metastasized tumors of F_ANXA7-down cells vs. that of F_{ANXA7-control} cells.
P-value 2 shows the difference within the group. ^◆The expression of Annexin A7 in primary tumors of F_{ANXA7-control} cells vs. that of lymph node metastasized tumors. ^■The expression of Annexin A7 in lymph node metastasized tumors of F_ANXA7-down cells vs. that of primary tumors. ^●The expression of Annexin A7 in lymph node metastasized tumors of P_{ANXA7-control} cells vs. that of primary tumors.

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