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Table 5 Prognostic factors for overall survival in patients with HCC

From: The Glasgow Prognostic Score, an inflammation based prognostic score, predicts survival in patients with hepatocellular carcinoma

 

Univariate analysis

Multivariate analysis

Variable

P-value

Hazard ratio (95% CI )

P-value

Age

0.24

  

Sex (male/female)

0.35

  

AST

<0.0001

  

ALT

0.06

  

Total serum bilirubin

<0.0001

  

Albumin

<0.0001

  

CRP

<0.0001

  

WBC

0.42

  

Platelet count

0.04

  

Prothrombin time

0.09

  

α-fetoprotein

<0.0001

  

Child-Pugh grade (A/B/C)

<0.0001

  

GPS (0/1/2)

<0.0001

1.773 (1.239-2.539)

0.002

mGPS (0/1/2)

<0.0001

  

CLIP score (0/1/2/3/4/5/6)

<0.0001

2.243 (1.784-2.820)

<0.0001

JIS score (0/1/2/3/4/5)

<0.0001

 

BCLC score (0/A/B/C/D)

<0.0001

 

tumour stage (І/ІІ/ІІІ/ІV)

<0.0001

 

Maximal tumour diameter (mm)

<0.0001

 

tumour number (solitary/multiple)

<0.0001

 

Vascular invasion (absent/present)

<0.0001

 

Extrahepatic metastasis (absent/prsent)

0

 
  1. Univariate and multivariate analysis.
  2. Abbreviaions: AST = aspartate aminotransferase; ALT = alanine aminotransferase; CRP = C-reactive protein;WBC = white blood cell count;
  3. CLIP = Cancer of the Liver Italian Program; JIS = Japan Integrated Staging score; BCLC = Barcelona Clinic Liver Cancer;
  4. GPS = Glasgow Prognostic Score; mGPS = modified GPS.