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Table 5 Prognostic factors for overall survival in patients with HCC

From: The Glasgow Prognostic Score, an inflammation based prognostic score, predicts survival in patients with hepatocellular carcinoma

  Univariate analysis Multivariate analysis
Variable P-value Hazard ratio (95% CI ) P-value
Age 0.24   
Sex (male/female) 0.35   
AST <0.0001   
ALT 0.06   
Total serum bilirubin <0.0001   
Albumin <0.0001   
CRP <0.0001   
WBC 0.42   
Platelet count 0.04   
Prothrombin time 0.09   
α-fetoprotein <0.0001   
Child-Pugh grade (A/B/C) <0.0001   
GPS (0/1/2) <0.0001 1.773 (1.239-2.539) 0.002
mGPS (0/1/2) <0.0001   
CLIP score (0/1/2/3/4/5/6) <0.0001 2.243 (1.784-2.820) <0.0001
JIS score (0/1/2/3/4/5) <0.0001  
BCLC score (0/A/B/C/D) <0.0001  
tumour stage (І/ІІ/ІІІ/ІV) <0.0001  
Maximal tumour diameter (mm) <0.0001  
tumour number (solitary/multiple) <0.0001  
Vascular invasion (absent/present) <0.0001  
Extrahepatic metastasis (absent/prsent) 0  
  1. Univariate and multivariate analysis.
  2. Abbreviaions: AST = aspartate aminotransferase; ALT = alanine aminotransferase; CRP = C-reactive protein;WBC = white blood cell count;
  3. CLIP = Cancer of the Liver Italian Program; JIS = Japan Integrated Staging score; BCLC = Barcelona Clinic Liver Cancer;
  4. GPS = Glasgow Prognostic Score; mGPS = modified GPS.