Skip to main content

Table 2 Univariate Cox proportional hazards regression analysis for overall survival and relapse-free survival

From: Expression of nerve growth factor and heme oxygenase-1 predict poor survival of breast carcinoma patients

Characteristics No. OS    RFS   
   HR 95% CI P HR 95% CI P
Age, y, ≥ 50 (vs. < 50) 41/145 2.928 1.620-5.293 < 0.001 1.914 1.112-3.295 0.019
TNM stage, I 29/145 1   0.016 1   0.197
        II 97/145 2.482 0.874-7.046 0.088 1.386 0.644-2.983 0.403
      III and IV 19/145 5.154 1.614-16.457 0.006 2.288 0.902-5.799 0.081
Histologic grade, 1 49/145 1   0.014 1   0.087
        2 67/145 1.218 0.575-2.579 0.607 1.147 0.598-2.198 0.680
        3 29/145 2.818 1.293-6.139 0.009 2.077 1.027-4.203 0.042
HER2, positive (vs. negative) 40/145 2.765 1.525-5.012 < 0.001 2.596 1.511-4.461 < 0.001
ER, positive (vs. negative) 80/145 0.691 0.382-1.250 0.222 0.911 0.533-1.557 0.733
NGF, positive (vs. negative) 45/145 4.674 2.541-8.598 < 0.001 3.55 2.074-6.076 < 0.001
HO1, positive (vs. negative) 71/145 6.101 2.832-13.143 < 0.001 3.476 1.914-6.314 < 0.001
NGF/HO1, NGF-/HO1- 69/145 1   < 0.001 1   < 0.001
      NGF-/HO1+ 31/145 5.019 1.855-13.578 0.001 2.935 1.338-6.436 0.007
      NGF+/anyHO1 45/145 9.717 4.003-23.586 < 0.001 5.41 2.754-10.625 < 0.001