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Table 1 Association of the expression of NGF and HO1 with clinicopathological factors

From: Expression of nerve growth factor and heme oxygenase-1 predict poor survival of breast carcinoma patients

Characteristics

 

No.

NGF

 

HO1

 
   

Positive

P

Positive

P

Age, y

<50

104

27 (26%)

0.035

45 (43%)

0.029

 

≥50

41

18 (44%)

 

26 (63%)

 

TNM stage

I

29

9 (31%)

0.836

17 (59%)

0.507

 

II

97

28 (29%)

 

45 (46%)

 
 

III and IV

19

7 (37%)

 

9 (47%)

 

T stage

1

41

10 (24%)

0.424

22 (54%)

0.675

 

2

95

31 (33%)

 

44 (46%)

 
 

3 and 4

9

4 (44%)

 

5 (56%)

 

LN metastasis

Absence

83

26 (31%)

0.930

39 (47%)

0.582

 

Presence

62

19 (31%)

 

32 (52%)

 

Latent distant metastasis

Absence

112

28 (25%)

0.004

45 (40%)

< 0.001

 

Presence

33

17 (52%)

 

26 (79%)

 

Histologic type

Ductal

137

43 (31%)

0.704

67 (49%)

0.952

 

Lobular

8

2 (25%)

 

4 (50%)

 

Histologic grade

1

49

9 (18%)

0.020

20 (41%)

0.017

 

2

67

22 (33%)

 

30 (45%)

 
 

3

29

14 (48%)

 

21 (72%)

 

HER2

Negative

105

25 (24%)

0.002

42 (40%)

< 0.001

 

Positive

40

20 (50%)

 

29 (73%)

 

ER

Negative

65

28 (43%)

0.005

35 (54%)

0.289

 

Positive

80

17 (21%)

 

36 (45%)

 

PR

Negative

60

23 (38%)

0.110

34 (57%)

0.119

 

Positive

85

22 (26%)

 

37 (44%)

 

HO1

Negative

74

5 (7%)

< 0.001

  
 

Positive

71

40 (56%)

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