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Table 1 Association of the expression of NGF and HO1 with clinicopathological factors

From: Expression of nerve growth factor and heme oxygenase-1 predict poor survival of breast carcinoma patients

Characteristics   No. NGF   HO1  
    Positive P Positive P
Age, y <50 104 27 (26%) 0.035 45 (43%) 0.029
  ≥50 41 18 (44%)   26 (63%)  
TNM stage I 29 9 (31%) 0.836 17 (59%) 0.507
  II 97 28 (29%)   45 (46%)  
  III and IV 19 7 (37%)   9 (47%)  
T stage 1 41 10 (24%) 0.424 22 (54%) 0.675
  2 95 31 (33%)   44 (46%)  
  3 and 4 9 4 (44%)   5 (56%)  
LN metastasis Absence 83 26 (31%) 0.930 39 (47%) 0.582
  Presence 62 19 (31%)   32 (52%)  
Latent distant metastasis Absence 112 28 (25%) 0.004 45 (40%) < 0.001
  Presence 33 17 (52%)   26 (79%)  
Histologic type Ductal 137 43 (31%) 0.704 67 (49%) 0.952
  Lobular 8 2 (25%)   4 (50%)  
Histologic grade 1 49 9 (18%) 0.020 20 (41%) 0.017
  2 67 22 (33%)   30 (45%)  
  3 29 14 (48%)   21 (72%)  
HER2 Negative 105 25 (24%) 0.002 42 (40%) < 0.001
  Positive 40 20 (50%)   29 (73%)  
ER Negative 65 28 (43%) 0.005 35 (54%) 0.289
  Positive 80 17 (21%)   36 (45%)  
PR Negative 60 23 (38%) 0.110 34 (57%) 0.119
  Positive 85 22 (26%)   37 (44%)  
HO1 Negative 74 5 (7%) < 0.001   
  Positive 71 40 (56%)