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Table 2 Quantitative PCR measurements of LATs mRNAs and pS6K protein densitometry results

From: Increased expression of system large amino acid transporter (LAT)-1 mRNA is associated with invasive potential and unfavorable prognosis of human clear cell renal cell carcinoma

   Real time RT-PCR for mRNAs Western blotting for pS6K protein
    LAT1   LAT2   LAT3   LAT4   4h2Fc   Number = 18   
   Number = 82   P value   P value   P value   P value   P value    Number = 18
Tissue tumor n = 82 1.78 ± 3.95 < 0.0001 0.14 ± 0.72 < 0.0001 0.32 ± 0.31 < 0.0001 0.79 ± 0.53 0.2199 0.55 ± 0.39 0.1496 n = 18 3.03 ± 1.91 3.03 ± 1.91
non-tumor n = 82 0.42 ± 1.36 0.74 ± 0.76 0.69 ± 0.55 0.87 ± 0.53 0.81 ± 0.85 n = 18 1.27 ± 0.37
Grade G1 n = 17 1.56 ± 2.33 0.0023 0.04 ± 0.03   0.29 ± 0.29 0.6275 0.87 ± 0.45 0.1214 0.62 ± 0.38 0.6340 n = 3 3.84 ± 2.25 0.3596
G2 n = 41 1.36 ± 4.61 0.07 ± 0.07 0.9112 0.35 ± 0.36 0.90 ± 0.59 0.55 ± 0.38 n = 9 2.63 ± 1.66
G3 n = 24 2.75 ± 3.18 0.34 ± 1.32   0.30 ± 0.20 0.55 ± 0.36 0.54 ± 0.43 n = 6 4.27 ± 1.99
pT stage pT1-2 n = 50 0.85 ± 1.58 0.0004 0.06 ± 0.06 0.556 0.34 ± 0.36 0.9583 0.85 ± 0.55 0.1103 0.54 ± 0.37 09280 n = 10 2.48 ± 1.12 0.0849
  pT3-4 n = 32 3.24 ± 5.76 0.28 ± 1.15 0.30 ± 0.20 0.68 ± 0.47 0.57 ± 0.43 n = 8 3.64 ± 2.21
Microscopic vascular invasion v0 n = 49 0.88 ± 1.60 0.0012 0.06 ± 0.06 0.7122 0.31 ± 0.34 0.3869 0.79 ± 0.50 0.6330 0.55 ± 0.40 0.9582 n = 10 2.77 ± 1.12 0.2087
v1 n = 33 3.11 ± 5.70 0.27 ± 1.13 0.35 ± 0.26 0.78 ± 0.57 0.55 ± 0.39 n = 8 3.66 ± 2.33
Metastasis M0 n = 60 1.73 ± 4.34 0.0462 0.08 ± 0.13 0.5461 0.34 ± 0.22 0.4314 0.83 ± 0.53 0.6125 0.58 ± 0.29 0.3429 n = 9 2.11 ± 1.24 0.0083
M1 n = 22 2.02 ± 2.69 0.17 ± 0.84 0.32 ± 0.33 0.78 ± 0.53 0.55 ± 0.42 n = 9 3.84 ± 2.05
  1. Data show mean ± S.D.