Table 2 Quantitative PCR measurements of LATs mRNAs and pS6K protein densitometry results

Tissue

tumor

n = 82

1.78 ± 3.95

< 0.0001

0.14 ± 0.72

< 0.0001

0.32 ± 0.31

< 0.0001

0.79 ± 0.53

0.2199

0.55 ± 0.39

0.1496

n = 18

3.03 ± 1.91

3.03 ± 1.91

non-tumor

n = 82

0.42 ± 1.36

0.74 ± 0.76

0.69 ± 0.55

0.87 ± 0.53

0.81 ± 0.85

n = 18

1.27 ± 0.37

Grade

G1

n = 17

1.56 ± 2.33

0.0023

0.04 ± 0.03

0.29 ± 0.29

0.6275

0.87 ± 0.45

0.1214

0.62 ± 0.38

0.6340

n = 3

3.84 ± 2.25

0.3596

G2

n = 41

1.36 ± 4.61

0.07 ± 0.07

0.9112

0.35 ± 0.36

0.90 ± 0.59

0.55 ± 0.38

n = 9

2.63 ± 1.66

G3

n = 24

2.75 ± 3.18

0.34 ± 1.32

0.30 ± 0.20

0.55 ± 0.36

0.54 ± 0.43

n = 6

4.27 ± 1.99

pT stage

pT1-2

n = 50

0.85 ± 1.58

0.0004

0.06 ± 0.06

0.556

0.34 ± 0.36

0.9583

0.85 ± 0.55

0.1103

0.54 ± 0.37

09280

n = 10

2.48 ± 1.12

0.0849

pT3-4

n = 32

3.24 ± 5.76

0.28 ± 1.15

0.30 ± 0.20

0.68 ± 0.47

0.57 ± 0.43

n = 8

3.64 ± 2.21

Microscopic vascular invasion

v0

n = 49

0.88 ± 1.60

0.0012

0.06 ± 0.06

0.7122

0.31 ± 0.34

0.3869

0.79 ± 0.50

0.6330

0.55 ± 0.40

0.9582

n = 10

2.77 ± 1.12

0.2087

v1

n = 33

3.11 ± 5.70

0.27 ± 1.13

0.35 ± 0.26

0.78 ± 0.57

0.55 ± 0.39

n = 8

3.66 ± 2.33

Metastasis

M0

n = 60

1.73 ± 4.34

0.0462

0.08 ± 0.13

0.5461

0.34 ± 0.22

0.4314

0.83 ± 0.53

0.6125

0.58 ± 0.29

0.3429

n = 9

2.11 ± 1.24

0.0083

M1

n = 22

2.02 ± 2.69

0.17 ± 0.84

0.32 ± 0.33

0.78 ± 0.53

0.55 ± 0.42

n = 9

3.84 ± 2.05