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Figure 3 | BMC Cancer

Figure 3

From: SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes

Figure 3

Endogenous expression of SORBS2 and p16 INK4A during in vitro passaging of primary keratinocytes. Immunocytochemical staining of endogenously expressed SORBS2 and p16INK4A in primary human keratinocytes of the donor FK09-9 (A) at passage 5 and (B) at passage 7 was performed. Strong endogenous expression of p16INK4a and SORBS2 correlated with a near senescent stage of the cells (B). (a, c magnification ×100; b, d magnification ×200)

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