Figure 2From: Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer Opposite methylation and expression patterns of MTO1 vs. MRPL41 according to estrogen receptor (ER) status in breast cancer cell lines. Methylation and expression of MTO1 (A and C) and MRPL41 (B and D) were examined by real-time methylation-specific polymerase chain reaction (PCR) and RT-PCR, respectively, in ER(+) and ER(-) breast cancer cell lines. Each sample was examined in three independent reactions, and the average relative level is presented with the standard error.Back to article page