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Table 3 Multivariate adjusted geometric means and 95% confidence intervals of bone mineral density (BMD) by quartiles of lean mass and fat mass by body fatness and sarcopenia status

From: Disentangling the body weight-bone mineral density association among breast cancer survivors: an examination of the independent roles of lean mass and fat mass

Ā 

Women with fat mass indexā€‰<ā€‰= 12.9Ā kg/m2(nā€‰=ā€‰474)

Women with fat mass index >ā€‰12.9Ā kg/m2(nā€‰=ā€‰125)

Ā 

Quartile (Q)

N

Geometric mean (95% CI) of BMD (g/cm2)

Quartile (Q)

N

Geometric mean (95% CI) of BMD (g/cm2)

Lean Mass (kg)

Ā Ā Ā Ā Ā Ā 
Ā 

Q1 (26ā€“35)

118

1.07 (1.04, 1.11)

Q1 (31ā€“38)

31

1.08 (1.04, 1.12)

Ā 

Q2 (35ā€“38)

119

1.09 (1.06, 1.13)

Q2 (38ā€“43)

31

1.08 (1.04, 1.12)

Ā 

Q3 (38ā€“41)

119

1.10 (1.06, 1.13)

Q3 (43ā€“47)

32

1.13 (1.09, 1.17)

Ā 

Q4 (41ā€“57)

118

1.13 (1.09, 1.17)

Q4 (47ā€“70)

31

1.15 (1.11, 1.19)

Ā 

p-trend

Ā 

<ā€‰0.0001

p-trend

Ā 

0.004

Ā 

Women without sarcopenia (nā€‰=ā€‰515) 2

Women with sarcopenia (nā€‰=ā€‰84) 2

Fat Mass (kg)

Ā Ā Ā Ā Ā Ā 
Ā 

Q1 (3ā€“20)

128

1.08 (1.05, 1.12)

Q1 (6ā€“17)

21

1.04 (0.97, 1.12)

Ā 

Q2 (20ā€“26)

129

1.11 (1.07, 1.14)

Q2 (17ā€“20)

21

1.07 (0.97, 1.17)

Ā 

Q3 (26ā€“33)

129

1.11 (1.07, 1.14)

Q3 (20ā€“24)

21

1.08 (0.99, 1.18)

Ā 

Q4 (33ā€“68)

129

1.15 (1.11, 1.19)

Q4 (24ā€“34)

21

1.09 (0.99, 1.20)

Ā 

p-trend

Ā 

<ā€‰0.0001

p-trend

Ā 

0.18

  1. 1Adjusted for age, menopausal status, postmenopausal hormone therapy use, treatment at diagnosis, tamoxifen use, race/ethnicity, study site.
  2. 2Sarcopenia status determined by appendicular lean mass index; without sarcopenia: ā‰„ā€‰5.45Ā kg/m2, sarcopenic: <ā€‰5.45Ā kg/m2.