Figure 3
Oxaliplatin-induced motor nerve hyperexcitability. (A) Representative example of abnormal spontaneous high frequency motor unit action potentials detected on electromyography (EMG) on day 2 after oxaliplatin treatment (severity grade 4). (B) EMG motor nerve hyperexcitability score by study treatment on day 2 after treatment cycles one and two given with placebo (blue circle) or Ca/Mg (gold diamond) infusions. Individual scores for each patient are joined by the lines. EMG scores were calculated as described in the methods section.