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Table 3 Multivariate survival analysis by tumor localization, adjusted for age and gender

From: An explorative analysis of ERCC1-19q13 copy number aberrations in a chemonaive stage III colorectal cancer cohort

  

Tumor Localization

  

Colon

Rectal

Clinical endpoint

Covariate

HR

95% CI

p-value

HR

95% CI

p-value

OS

ERCC1 -19q13

0.32

0.14-0.75

0.01

0.82

0.35-1.95

0.66

ERCC1 -19q13/CEN-2

0.37

0.16-0.83

0.02

1.01

0.425-2.25

0.98

ERCC1 -19q13 gain

0.45

0.20-1.00

0.049

1.01

0.59-1.75

0.97

TTR

ERCC1 -19q13

0.34

0.12-1.00

0.0499

0.87

0.36-2.15

0.77

ERCC1 -19q13/CEN-2

0.24

0.09-0.70

0.01

0.87

0.36-2.14

0.77

ERCC1 -19q13 gain

0.42

0.16-1.07

0.07

1.00

0.56-1.77

0.99

LR a

ERCC1 -19q13

-

-

-

0.68

0.20-2.28

0.53

ERCC1 -19q13/CEN-2

-

-

-

0.91

0.28-3.04

0.88

 

ERCC1 -19q13 gain

-

-

-

0.73

0.33-1.60

0.42

  1. aRectal cancer patients only.