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Figure 7 | BMC Cancer

Figure 7

From: Selective apoptosis induction in MCF-7 cell line by truncated minimal functional region of Apoptin

Figure 7

Apoptosis assay in non-cancerous Chang cells. Chang cells that were microinjected with A) PrVP3, B) PrVP3A1-69N1N2, C) PrVP3A1-46N1N2, D) PrVP3A1-31N1N2, E) PrVP3A32-69N1N2, F) PrVP3A32-62N1N2, G) negative control, PrMBP and H) non-injected cells were analyzed by Annexin V assay at 5 hr and 15 hr. Both green and red fluorescence signal in the cell showed the presence of necrotic cells (yellow arrow). No apoptotic cell was detected in A-D and G. Green fluorescence in E and F showed the presence of apoptotic cells at 15 hr time point (red arrow).

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