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Table 1 Genotypes of s-BOTs and corresponding implants

From: KRAS, BRAF genotyping reveals genetic heterogeneity of ovarian borderline tumors and associated implants

 

s-BOT(s)

Implant(s)

Patient

 

KRAS

BRAF

Implants (n)

Mutation profiles (n)

KRAS

BRAF

1

Unilateral

wt

wt

1

1

wt

wt

2

Bilateral

wt

p.V600E

4

3

wt

wt

1

wt

p.V600E

wt

p.V600E

3

Unilateral

p.G12D

wt

1

1

p.G12D

p.V600E

4

Unilateral

wt

wt

4

4

wt

wt

5

Bilateral

wt

p.V600E

2

1

wt

wt

1

p.G12D

wt

wt

p.V600E

6

Unilateral

wt

p.V600E

2

1

wt

wt

1

wt

p.V600E

7

Unilateral

wt

wt

3

3

wt

wt

8

Bilateral

wt

wt

2

2

wt

wt

wt

wt

9

Unilateral

wt

p.V600E

2

1

wt

p.V600E

1

wt

wt

10

Unilateral

p.G12A

p.V600E

1

1

wt

p.V600E

11

Bilateral

wt

p.V600E

2

1

p.G12V

p.V600E

1

wt

p.V600E

p.G12V

wt

12

Bilateral

p.G12A

p.V600E

3

1

p.G12A

p.V600E

2

wt

p.V600E

p.G12A

p.V600E

13

Unilateral

wt

wt

2

2

wt

p.V600E

14

Unilateral

p.G12V

wt

1

1

wt

p.V600E

15

Bilateral

p.G12V

p.V600E

19

11

p.G12V

wt

1

wt

p.V600E

p.G12V

wt

1

p.G12V

p.V600E

     

6

wt

wt

  1. n.a. = not applicable. The total number of implants diagnosed in each patient is displayed in the “number of implants” column and the count of how often each mutation profile was observed is specified in the “mutation profiles” column.