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Figure 9 | BMC Cancer

Figure 9

From: Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin

Figure 9

Expression of LGR-5 in histological sections of rat colon as assessed by immunofluorescence technique. Panel A: a single stained cell (white arrow) at the lower compartment of the crypt in normal mucosa. Panel B: multiple positive cells at the base of normal crypts. Panel C: LGR-5 over-expression in a preneoplastic lesion MDF. Panel D: Magnification of the white inset in panel C showing: LGR-5 expressing cells (yellow arrow), cells expressing β-catenin in the nucleus (green arrow) and a cell co-expressing LGR-5 and nuclear β-catenin (white arrow). Original magnification 400x.

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