Figure 5

Venn diagram comparing significantly changed genes in MCF7, BT474 cell lines and AI-treated patients. (A) Genes significantly down-regulated in response to estrogen deprivation after 6 weeks vs. control in MCF7 and BT474 cells compared with those significantly down-regulated in AI-treated patients (B) Genes significantly up-regulated in response to estrogen deprivation after 6 weeks vs. control in MCF7 and BT474 cells compared with those significantly up-regulated in AI-treated patients.