Figure 4From: Clinical instability of breast cancer markers is reflected in long-term in vitro estrogen deprivation studies Cell cycle genes affected in estrogen deprived cells. Red and blue boxes indicate up- and down regulated gene expression in response to estrogen deprivation relative to untreated control. Small circles (red and blue) mark a statistically significant increase or decrease in expression. (A) MCF7 cells at 2Â days after estrogen deprivation versus control cells. (B) BT474 cells at 6Â weeks after estrogen deprivation versus control cells.Back to article page