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Table 2 Relationship between p-mTOR expression and activation of ALK and AKT

From: Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma

 

p-mTOR + (n = 57)

p-mTOR- (n = 14)

p-value

No. of patients

%

No. of patients

%

ALK (n = 71)

     

 ALK+

39 of 57

68

5 of 14

36

0.024*

 ALK-

18 of 57

32

9 of 14

64

 

p-AKT (n = 71)

     

 p-AKT+

47 of 57

83

7 of 14

50

0.011*

 p-AKT-

10 of 57

17

7 of 14

50

 

ALK + (n = 44)

     

 ALK(n + c)

30 of 39

77

3 of 5

60

0.431

 ALK(c)

9 of 39

23

2 of 5

40

 
  1. *Statistically significant value.
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BMC Cancer

ISSN: 1471-2407

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