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Table 1 Relationship between p-AKT expression and ALK activation in ALCL

From: Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma

 

p-AKT + (n = 54)

p-AKT- (n = 17)

p-value

No. of patients

%

No. of patients

%

ALCL (n = 71)

     

 ALK+

38 of 54

70

6 of 17

35

 

 ALK-

16 of 54

30

11 of 17

65

0.009*

ALK + (n = 44)

     

 ALK (n + c)

29 of 39

74

4 of 5

80

 

 ALK (c)

10 of 39

26

1 of 5

20

0.779

  1. * Statistically significant value.
  2. ALK(n + c) indicates ALK + with both nucleus and cytoplasmic staining; ALK(c), ALK + with cytoplasmic staining only.