High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer

Table 5 Multivariate Cox proportional hazard analysis for disease-specific survival

Characteristics	β	SE	Wald	P-value	HR	95.0% CI
Characteristics	β	SE	Wald	P-value	HR	Lower	Upper
AGE	−0.10	0.35	0.03	0.85	0.94	0.47	1.87
GGH	1.20	0.53	5.81	0.02	3.62	1.27	10.3
Histological type	−0.60	0.39	3.09	0.07	0.51	0.24	1.08
BRE grade	−0.05	0.18	0.07	0.78	0.95	0.67	1.34
ER/PR status	0.14	0.35	0.18	0.67	1.12	0.59	2.29
HER2/neu status	−0.40	0.38	0.95	0.33	0.69	0.32	1.46
Pathological size	−0.01	0.01	0.23	0.63	0.10	0.97	1.02
Axillary lymph nodes	0.05	0.36	0.02	0.87	1.06	0.52	2.16

β: Regression coefficient; SE: standard error of β; HR: hazard ratio; and CI: confidence interval. BRE: Bloom, Richardson, Elston/ Ellis; ER/PR: Estrogen/Progesterone receptor.

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