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Table 3 The association of GGH, FAAH, PIR and TAF5L to the clinicopathological characteristics in addition to clinical outcomes

From: High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer

Characteristics FAAH PIR TAF5L GGH
Negative Positive Negative Positive Negative Positive Negative Positive
8 (100) 64 (100) 11 (100) 61 (100) 40 (100) 32 (100) 18 (100) 56 (100)
Survival ≥8 yrs 4 (12) 29 (88) 4 (12) 29 (88) 18 (55) 15 (45) 11 (36) 22 (64)
Survival <8 yrs 4 (10) 35 (90) 7 (18) 32 (82) 22 (57) 17 (43) 5 (16) 34 (84)
  P = 0.55   P = 0.53   P = 1   P = 0.037  
Recurrence         
No 3 (12) 22 (88) 2 (8) 23 (92) 16 (64) 9 (36) 9 (36) 16 (64)
Yes 0 (0) 18 (100) 2 (11) 16 (89) 7 (39) 11 (61) 0 (0) 18 (100)
  P = 0.29   P = 0.87   P = 0.12   P = 0.009  
Age         
27-59 2 (9) 20 (91) 3 (14) 19.(86) 12 (55) 10 (45) 6 (27) 16 (73)
≥60 16 (73) 44 (88) 8 (16) 42 (84) 28 (56) 22 (44) 12 (24) 38 (76)
  P = 0.54   P = 1   P = 1   P = 0.78  
BRE grade         
I-II 5 (14) 31 (86) 4 (11) 32 (89) 16 (44) 20 (66) 15 (42) 21 (58)
III 3 (8) 33 (92) 7 (19) 29 ( 81) 24 (67) 12 (33) 3 (8) 33 (92)
  P = 0.71   P = 0.51   P = 0.06   P <0.001  
Axillary lymph node status         
Negative 2 (8) 22 (92) 7 (29) 17 (71) 14 (58) 10 (42) 5 (21) 19 (79)
Positive 6 (13) 42 (87) 4 (8) 44 (92) 26 (54) 22 (46) 13 (27) 35 (73)
  P = 0.71   P = 0.034   P = 0.81   P = 0.88  
No. of axillary lymph nodes         
1-3 0 (0) 23 (100) 1 (4) 22 (96) 13 (43) 17 (57) 6 (26) 17 (74)
≥4 6 (24) 19 (76) 3 (12) 22 (88) 10 (56) 8 (44) 7 (28) 18 (72)
  P = 0.023   P = 0.6   P = 0.56   P = 0.63  
ER/PR status         
Negative 5 (15) 29 (85) 4 (12) 30 (88) 19 (56) 15 (44) 10 (41) 27 (59)
Positive 3 (8) 35 (92) 7 (18) 31.(82) 21 (55) 17 (45) 4 (10) 34 (90)
  P = 0.46   P = 0.52   P = 0.26   P = 0.01  
HER2/ neu status         
Negative 5 (14) 32 (86) 7 (19) 30 (81) 20 (54) 17 (46) 10 (71) 4 (29)
Positive 1 (5) 21 (95) 2 (9) 20 (91) 13 (59) 9 (41) 27 (60) 18 (40)
  P = 0.4   P = 0.46   P = 0.79   P = 0.53  
FAAH         
Negative    2 (18) 9 (82) 4 (50) 4 (50) 5 (28) 13 (72)
Positive    6 (10) 55 (90) 36 (56) 28 (44) 3 (6) 51 (94)
  -   P = 0.6   P = 1   P = 0.02  
PIR         
Negative 2 (25) 6 (75)    7 (64) 4 (36) 2 (11) 16 (89)
Positive 9 (14) 55 (86)    33 (54) 28 (46) 9 (17) 45 (83)
  P = 0.6   -   P = 0.74   P = 0.72  
TAF5L         
Negative 4 (10) 36 (90) 3 (27) 8 (73)    5 (28) 13 (72)
Positive 4 (13) 28 (87) 13 (21) 48 (79)    11 (20) 43 (80)
  P = 1   P = 0.7   -   P = 0.53  
GGH         
Negative 5 (63) 3 (37) 2 (18) 9 (82) 8 (44) 10 (66)   
Positive 13 (20) 51 (80) 16 (26) 45 (74) 32 (59) 22 (41)   
  P = 0.02   P = 0.72   P = 0.53   -