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Table 2 Expression of GAGE, NY-ESO-1 and SP17 in human NSCLC

From: Analysis of GAGE, NY-ESO-1 and SP17 cancer/testis antigen expression in early stage non-small cell lung carcinoma

Tumor expression of antigen

Histotype

All NSCLC specimens (n = 169)

Adenocarcinoma (n = 81)

Squamous cell carcinoma (n = 88)*

p-value

GAGE

15 (18.5%)

29 (33.0%)

0.19

44 (26.0%)

>1% - ≤ 10%

5 (6.2%)

5 (5.7%)

 

>10% - ≤ 50%

2 (2.5%)

4 (4.6%)

 

>50%

8 (9.9%)

20 (22.7%)

0.02

NY-ESO-1

8 (9.9%)

12 (13.6%)

0.49

20 (11.8%)

>1% - ≤ 10%

2 (2,5%)

1 (1.1%)

  

>10% - ≤ 50%

2 (2.5%)

1 (1.1%)

  

>50%

4 (4.9%)

10 (11.4%)

0.13

 

SP17

4 (4.9%)

4 (4.6%)

0.76

8 (4.7%)

>1% - ≤ 10%

4 (4.9%)

4 (4.6%)

>10% - ≤ 50%

0

0

>50%

0

0

  1. * The survival of the four NOS patients resembled that of patients with squamous cell carcinoma and were therefore included in this group for statistical analysis.