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Table 4 Doses that yielded the best overall responses

From: Phase I dose-finding study of cabazitaxel administered weekly in patients with advanced solid tumours

 

Best overall responsea

Planned dose level, mg/m2

Investigator’s response

Response review meeting (expert)

Final evaluation

8.4

PR

PR

PR

PR

NC

NC

10

NCb

NCc

NC c

12

PR

PR

PR

  1. a Each response represents one patient. b CR at cycle 2. c PR at cycle 2.
  2. CR complete response, PR partial response, NC no change.