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Table 2 Statistical analysis of the occurrence of NBN p.I171V mutation in leukemia patients and controls

From: Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia

  

Leukemia n=220

Controls n=2400

OR [95% CI]

p

Gene

Mutation

ALL

AML

 

ALL

AML

ALL

AML

NBN

p.I171V

5

2

12

5.437 (1.894 – 15.60)

21.60 (4.631 – 100.7)

0.00041

0.00011

  

ALL+AML

 

ALL+AML

ALL+AML

NBN

p.I171V

7

12

6.540 (2.547 – 16.79)

0.00011

  1. 1Result statistically significant (P<0.05), OR (95% CI) -Odds ratio (95% confidence interval).
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BMC Cancer

ISSN: 1471-2407

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