Skip to main content

Table 2 Univariate survival analysis for Sirt1 expression and clinico-pathological parameters in PDAC

From: High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma

   Cases Events Mean survival (months) Standard error Log-rank-test (p-value)
Age at diagnosis <=65 years 56 42 50.1 10.5 0.564
  >65 years 57 47 25.1 4.4  
WHO stage I 11 8 29.4 9.8 0.001
  IIA 17 10 52.8 11.9  
  IIB 78 64 33.7 7.0  
  III 3 3 5.6 0.8  
  IV 4 4 11.9 4.1  
Tumor stage T1 / / / /  
  T2 22 17 29.6 6.8 0.003
  T3 88 69 39.6 7.3  
  T4 3 3 5.6 0.8  
Nodal status N0 30 20 43.3 8.8 0.060
  N1 83 69 32.2 6.6  
State of metastasis M0 109 85 42.4 6.8 0.268
  M1 4 4 11.9 4.1  
Grade G1 7 6 16.8 2.5 0.058
  G2 54 39 37.3 6.0  
  G3 52 44 29.7 7.9  
SIRT1-expression low 81 58 54.1 8.9 0.002
  high 32 31 13.0 1.7