Figure 1
From: High SIRT1 expression is a negative prognosticator in pancreatic ductal adenocarcinoma
Immunblots with the antibody against Sirt1. While endogenous Sirt1 levels were detected by the antibody, knockdown of Sirt1 by siRNA in MiaPaCa-2 and PANC-1 cells led to a complete abrogation of the immunosignal indicating that the antibody binds specifically to its target protein.