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Table 2 Identification of differentially expressed proteins in bladder tissue from normal human, non-muscle invasive and muscle-invasive bladder cancer patients

From: Does phosphorylation of cofilin affect the progression of human bladder cancer?

No Change folds Protein names Peptide sequences Score/SC1)(%) pI/Mr (kDa) theoretical (experimental) Accession No/database Known function
  Non-in1)/normal Invas1)/normal       
1 −31.16 −64.91 Myosin regulatory light chain 2 GNFNYVEFTR 32/5 4.80/19.7 P24844/SP Regulation of cell contractile activity
(4.75/21.1)
2 2.75 1.78 14-3-3 protein σ EMPPTNPIR 20/3 4.72/27.8 631131/NC Epithelial cell growth
(4.68/30.0) P31947/SP
3 −3.83 −3.65 Galectin-1 DSNNLCLHFNPR 141/16 5.34/14.7 30582389/NC Regulation of apoptosis, proliferation and differentiation
DGGAWGTEQR (4.80/15.3) P09382/SP
4 −2.92 −2.39 Lipid-binding AI DEPPQSPWDR 75/8 5.27/28.3 229513/NC Lipid binding protein
THLAPYSDELR (4.88/25.8)
5 −2.38 −3.31 Annexin V GTVTDFPGFDER 160/11 4.94/35.8 809189/NC Anticoagulant
LYDAYELK
FITIFGTR (4.78/34.1) P08758/SP
SEIDLFNIR
6 −3.78 −3.50 Transthyretin GSPAINVAVHVFR 196/41 5.33/12.8 339685/NC Transports of thyroxine
AADDTWEPFASGK
ALGISPFHEHAEVVFTANDSGPR (5.07/17.0) P02766/SP
7 1 4.56 Ferritin light KPAEDEWGKTPDAMK 130/32 5.65/16.3 182516/NC Iron homeostasis
Subunit KLNQALLDLHALGSAR (5.06/22.3) P02792/SP
LGGPEAGLGEYLFER
8 −2.97 −4.88 CARD-inhibitor of DPYPVSYLR 37/2 5.14/48.8 15617462/NC Inhibitor of NF-κB activation
NF-κB-activating (5.18/25.3)
Ligand
9 −4.44 −12.69 Actin prepeptide AGFAGDDAPR 85/11 5.19/36.8 178067/NC Cell motility
AVFPSIVGRPR (5.19/52.8) P62736/SP  
SYELPDGQVITIGNER
10 4.53 5.71 Macrophage capping protein EVQGNESDLFMSYFPR 76/8 5.32/38.5 21730367/NC Regulation of cytoplasmic and/or nuclear structures
QAALQVAEGFISR (5.40/39.6) P40121/SP
11 −1.86 −2.31 Macrophage capping protein EVQGNESDLFMSYFPR 117/12 5.32/38.5 21730367/NC Regulation of cytoplasmic and/or nuclear structures
QAALQVAEGFISR (5.70/39.6) P40121/SP
MQYAPNTQVEILPQGR
12 4.25 4.41 Cofilin AVLFCLSEDKK 98/21 8.26/18.4 P23528/SP Actin polymerization
     YALYDATYETK   (7.48/19.8)   
     HELQANCYEEVKDR     
  1. 1)non-in, non-muscle-invasive bladder cancer; invas, muscle-invasive bladder cancer; SC, sequencer coverage.