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Table 2 Identification of differentially expressed proteins in bladder tissue from normal human, non-muscle invasive and muscle-invasive bladder cancer patients

From: Does phosphorylation of cofilin affect the progression of human bladder cancer?

No

Change folds

Protein names

Peptide sequences

Score/SC1)(%)

pI/Mr (kDa) theoretical (experimental)

Accession No/database

Known function

 

Non-in1)/normal

Invas1)/normal

      

1

−31.16

−64.91

Myosin regulatory light chain 2

GNFNYVEFTR

32/5

4.80/19.7

P24844/SP

Regulation of cell contractile activity

(4.75/21.1)

2

2.75

1.78

14-3-3 protein σ

EMPPTNPIR

20/3

4.72/27.8

631131/NC

Epithelial cell growth

(4.68/30.0)

P31947/SP

3

−3.83

−3.65

Galectin-1

DSNNLCLHFNPR

141/16

5.34/14.7

30582389/NC

Regulation of apoptosis, proliferation and differentiation

DGGAWGTEQR

(4.80/15.3)

P09382/SP

4

−2.92

−2.39

Lipid-binding AI

DEPPQSPWDR

75/8

5.27/28.3

229513/NC

Lipid binding protein

THLAPYSDELR

(4.88/25.8)

5

−2.38

−3.31

Annexin V

GTVTDFPGFDER

160/11

4.94/35.8

809189/NC

Anticoagulant

LYDAYELK

FITIFGTR

(4.78/34.1)

P08758/SP

SEIDLFNIR

6

−3.78

−3.50

Transthyretin

GSPAINVAVHVFR

196/41

5.33/12.8

339685/NC

Transports of thyroxine

AADDTWEPFASGK

ALGISPFHEHAEVVFTANDSGPR

(5.07/17.0)

P02766/SP

7

1

4.56

Ferritin light

KPAEDEWGKTPDAMK

130/32

5.65/16.3

182516/NC

Iron homeostasis

Subunit

KLNQALLDLHALGSAR

(5.06/22.3)

P02792/SP

LGGPEAGLGEYLFER

8

−2.97

−4.88

CARD-inhibitor of

DPYPVSYLR

37/2

5.14/48.8

15617462/NC

Inhibitor of NF-κB activation

NF-κB-activating

(5.18/25.3)

Ligand

9

−4.44

−12.69

Actin prepeptide

AGFAGDDAPR

85/11

5.19/36.8

178067/NC

Cell motility

AVFPSIVGRPR

(5.19/52.8)

P62736/SP

 

SYELPDGQVITIGNER

10

4.53

5.71

Macrophage capping protein

EVQGNESDLFMSYFPR

76/8

5.32/38.5

21730367/NC

Regulation of cytoplasmic and/or nuclear structures

QAALQVAEGFISR

(5.40/39.6)

P40121/SP

11

−1.86

−2.31

Macrophage capping protein

EVQGNESDLFMSYFPR

117/12

5.32/38.5

21730367/NC

Regulation of cytoplasmic and/or nuclear structures

QAALQVAEGFISR

(5.70/39.6)

P40121/SP

MQYAPNTQVEILPQGR

12

4.25

4.41

Cofilin

AVLFCLSEDKK

98/21

8.26/18.4

P23528/SP

Actin polymerization

    

YALYDATYETK

 

(7.48/19.8)

  
    

HELQANCYEEVKDR

    
  1. 1)non-in, non-muscle-invasive bladder cancer; invas, muscle-invasive bladder cancer; SC, sequencer coverage.