| Level of tumor thrombus | Statistical significance (chi-square test or Mann–Whitney U test) | |||||
---|---|---|---|---|---|---|---|
Variables | Intra-renal vein | Infrahepatic IVC | Suprahepatic IVC | Intrapericardial IVC/ intracardiac extension | Unknown | Total | |
n | 148 | 101 | 20 | 11 | 8 | 292 | Â |
Gender (n) | |||||||
Male | 108 | 80 | 15 | 7 | 7 | 217 | n.s. |
Female | 44 | 21 | 5 | 4 | 1 | 75 | Â |
Age (years) | |||||||
Mean ± S.D. | 63.7 ± 10.8 | 60.8 ± 10.4 | 62.3 ± 11.8 | 60.6 ± 12.5 | 61.8 ± 11.4 | 62.4 ± 10.8 | n.s. |
Performance status (n) | |||||||
0 | 105 | 73 | 11 | 5 | 3 | 197 | n.s. |
1 | 18 | 11 | 6 | 2 | 2 | 39 | |
2 | 10 | 2 | 1 | 1 | 0 | 14 | |
3 | 2 | 4 | 0 | 1 | 0 | 7 | |
Unknown | 17 | 11 | 2 | 2 | 3 | 35 | Â |
ESR (mm) | |||||||
Mean ± S.D. | 56.5 ± 44.1 | 65.4 ± 43.7 | 81.7 ± 38.6 | 43.8 ± 57.2 | 93.3 ± 70.6 | 62.0 ± 44.6 | p < 0.05; intra-renal vein vs. suprahepatic IVC |
CRP (ng/ml) | |||||||
Mean ± S.D. | 3.7 ± 4.9 | 4.0 ± 5.7 | 5.3 ± 5.6 | 1.7 ± 1.4 | 7.2 ± 10.0 | 3.9 ± 5.4 | n.s. |
IAP (ug/ml) | |||||||
Mean ± S.D. | 796.9 ± 420.5 | 794.4 ± 328.2 | 1020.4 ± 438.7 | 828.2 ± 372.9 | 789 ± 475 | 813.2 ± 391.4 | p < 0.05; intra-renal vein, infrahepatic IVC vs. suprahepatic IVC |
Tumor size classification (n) | |||||||
<4Â cm | 17 | 5 | 1 | 2 | 0 | 25 | n.s. |
4-7Â cm | 40 | 22 | 5 | 4 | 2 | 73 | |
>7Â cm | 90 | 70 | 11 | 4 | 4 | 179 | |
Unknown | 5 | 4 | 3 | 1 | 2 | 15 | Â |
Tumor location (n) | |||||||
Right | 72 | 67 | 12 | 9 | 5 | 165 | n.s. |
Left | 76 | 33 | 8 | 2 | 1 | 120 | |
Bilateral | 2 | 1 | 0 | 0 | 0 | 3 | |
Missing data | 2 | 0 | 0 | 0 | 2 | 4 | Â |
Perinephric fat invasion (n) | |||||||
No | 56 | 38 | 12 | 5 | 3 | 114 | n.s. |
Yes | 21 | 17 | 3 | 1 | 1 | 43 | |
Unknown | 75 | 46 | 5 | 5 | 4 | 135 | Â |
Regional lymph node involvement (n) | |||||||
No | 74 | 29 | 10 | 4 | 1 | 118 | n.s. |
Yes | 27 | 23 | 3 | 2 | 6 | 61 | |
Unknown | 51 | 49 | 7 | 5 | 1 | 113 | Â |
Distant metastases (n) | |||||||
No | 100 | 60 | 12 | 8 | 3 | 183 | n.s. |
Yes | 47 | 32 | 4 | 3 | 5 | 91 | |
Unknown | 5 | 9 | 4 | 0 | 0 | 18 | Â |
Tumor nuclear grade (n) | |||||||
G1 | 15 | 9 | 2 | 1 | 0 | 27 | n.s. |
G2 | 103 | 52 | 14 | 6 | 4 | 179 | |
G3 | 29 | 38 | 4 | 3 | 1 | 75 | |
Unknown | 5 | 2 | 0 | 1 | 3 | 11 | Â |
Histopathologic category (n) | |||||||
Clear cell | 112 | 67 | 17 | 7 | 3 | 206 | n.s. |
Papillary, chromophobe, others | 28 | 29 | 3 | 4 | 3 | 67 | |
Spindle, sarcomatoid | 12 | 5 | 0 | 0 | 2 | 19 |