Figure 3
From: High-risk human papillomavirus (HPV) DNA sequences in metaplastic breast carcinomas of Mexican women
A case of a human papillomavirus ( HPV )- 16 - positive, estrogen receptor ( ER )- negative breast metaplastic carcinoma with chondroid differentiation , is illustrated ( Case 1 ) . Note the absence of brown colouration in the neoplastic cell nuclei, indicating the lack of ER immunoreactivity (anti-ER antibody, clone1D5). (Immunohistochemistry [IHC]; Original magnification 200×).