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Table 2 Incremental effectiveness and costs of adjuvant S-1 therapy (discount rate: 3% for both effectiveness and costs)

From: Cost-effectiveness of adjuvant chemotherapy for curatively resected gastric cancer with S-1

Period

S-1 therapy

Surgery alone

Incremental effectiveness and costs (95% CI)

Effectiveness

 

QALYs

  

5-year observation

3.11

2.84

0.27 (0.11 – 0.42)

10-year follow-up

5.08

4.45

0.64 (0.28 – 0.99)

Over lifetime

8.65

7.41

1.24 (0.48 – 1.96)

 

Costs ($)

  

5-year observation

10,802

7,408

3,389 (2,616 – 4,174)

10-year follow-up

12,110

8,523

3,585 (2,750 – 4,411)

Over lifetime

13,057

9,346

3,722 (2,911 – 4,512)

Incremental cost-effectiveness ratio

 

Cost ($) per QALY gained

(95% CI)

5-year observation

12,716

(6,428 – 34,018)

10-year follow-up

5,608

(2,855 – 14,569)

Over lifetime

3,016

(1,441 – 8,840)

  1. CI = confidence interval; QALYs = quality-adjusted life-years.