Figure 5
From: Expression of activator protein-1 (AP-1) family members in breast cancer
mRNA expression of Fra-1 in relation to ER status, PR status and breast cancer subtypes. The expression of Fra-1 is higher in tumors classified as ER negative and PR negative tumors compared with ER and PR positive tumors (p = 0.012 and p = 0.037, respectively) (A and B). In addition, Fra-1 was significantly higher expressed in triple-negative tumors compared with other groups (p = 0.039) (C). Gene expression (y-axis) was quantified by real-time PCR and normalized to UBC.