Suppression subtractive hybridization identified differentially expressed genes in lung adenocarcinoma: ERGIC3as a novel lung cancer-related gene

Table 2 Immunohistochemical staining of ERGIC3 in lung cancer tissues

Characteristic	ERGIC3⁻	ERGIC3⁺	P-value
Gender			0.279
Male	3/17 (18%)^#	14/17 (82%)
Female	1/18 (6%)	17/18 (94%)
Age, y			/
Median	55.9	53.5
Range	36-76	38-71
Smoking			0.323
No	1/17 (6%)	16/17 (94%)
Yes	3/18 (17%)	15/18 (83%)
Histological type			0.014*
AC	0	22/22 (100%)
SCC	4/13 (31%)	9/13 (69%)
TNM stage			0.419
I + II	3/20 (15%)	17/20 (85%)
III + IV	1/15 (7%)	14/15 (93%)
Differentiation			0.006*
Poor	4/11 (36%)	7/11 (64%)
Well or Moderate	0	24/24 (100%)

Statistical significance was determined by the Fisher’s exact test of chi-square test (two-tailed); #: Number of cases applicable/total number of cases examined (with percent in parenthesis); *: Statistically significant, P < 0.05.
Abbreviations: SCC: squamous cell carcinoma; AC: adenocarcinoma; y: year.

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